Document Detail

Comparative role of neuropsychological testing in the presurgical evaluation of children with medically intractable epilepsies.
MedLine Citation:
PMID:  19252915     Owner:  NLM     Status:  MEDLINE    
PURPOSE: In the present study, we evaluated the preoperative demographic, clinical, and neuropsychological variables that could predict postoperative seizure outcome in a group of pediatric epileptic patients. MATERIALS AND METHODS: We studied 40 consecutive pediatric patients, ages ranging from 6 to 16 years, that underwent resective surgery for the treatment of medically intractable epilepsy at the Clinical Hospital of Ribeirão Preto School of Medicine. We performed ictal electroencephalography (EEG), interictal EEG, magnetic resonance imaging (MRI), and a preoperative neuropsychological assessment in the presurgical workup. RESULTS: The following factors were correlated with seizure outcome: (1) duration of epilepsy, (2) surgery localization, (3) localized Neuropsychological (NPS) Evaluation, (4) ictal EEG, (5) interictal EEG, and (6) MRI. Mental retardation, NPS tests, and the other demographic variables failed to correlate with seizure reduction. CONCLUSIONS: The identification of predictor variables of epilepsy surgery outcome could improve the epileptic prognosis and guarantee the children's full potential development.
Cecília Souza-Oliveira; Sara Escorsi-Rosset; Marino Muxfeldt Bianchin; Vera Cristina Terra; Lauro Wichert-Ana; Hélio Rubens Machado; Américo Ceiki Sakamoto
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-02-28
Journal Detail:
Title:  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery     Volume:  25     ISSN:  1433-0350     ISO Abbreviation:  Childs Nerv Syst     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-05     Completed Date:  2009-08-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8503227     Medline TA:  Childs Nerv Syst     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  875-80     Citation Subset:  IM    
Department of Neurology, Psychiatry and Psychology, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
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MeSH Terms
Brain / physiopathology,  surgery
Cognition Disorders / etiology
Epilepsy / diagnosis*,  physiopathology,  surgery*
Follow-Up Studies
Magnetic Resonance Imaging
Neuropsychological Tests*
Preoperative Care*
Seizures / diagnosis,  physiopathology,  surgery
Severity of Illness Index
Treatment Outcome

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