Document Detail


Comparative population analysis of Klebsiella pneumoniae strains with extended-spectrum β-lactamases colonizing patients in rehabilitation centers in four countries.
MedLine Citation:
PMID:  23403417     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The international project MOSAR was conducted in five rehabilitation centers; patients were screened for rectal carriage of extended-spectrum β-lactamase (ESBL)-producing members of the Enterobacteriaceae. Among 229 Klebsiella pneumoniae isolates, four clonal groups (CG) or complexes (CC) prevailed: CG17 in France, CG101 in Italy, CG15 in Spain, and CC147 in Israel. ESBLs, mainly CTX-Ms, were produced by 226 isolates; three isolates expressed AmpC-like cephalosporinases. High genetic diversity of K. pneumoniae populations was observed, with specific characteristics at each center.
Authors:
A Baraniak; R Izdebski; J Fiett; E Sadowy; A Adler; M Kazma; J Salomon; C Lawrence; A Rossini; A Salvia; J Vidal Samso; J Fierro; M Paul; Y Lerman; S Malhotra-Kumar; C Lammens; H Goossens; W Hryniewicz; C Brun-Buisson; Y Carmeli; M Gniadkowski;
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-02-12
Journal Detail:
Title:  Antimicrobial agents and chemotherapy     Volume:  57     ISSN:  1098-6596     ISO Abbreviation:  Antimicrob. Agents Chemother.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-15     Completed Date:  2013-09-06     Revised Date:  2013-10-08    
Medline Journal Info:
Nlm Unique ID:  0315061     Medline TA:  Antimicrob Agents Chemother     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1992-7     Citation Subset:  IM    
Affiliation:
National Medicines Institute, Warsaw, Poland.
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MeSH Terms
Descriptor/Qualifier:
France
Genetics, Population
Israel
Italy
Klebsiella pneumoniae / classification,  enzymology*,  genetics
Rehabilitation Centers*
Spain
beta-Lactamases / genetics,  metabolism*
Chemical
Reg. No./Substance:
EC 3.5.2.6/beta-Lactamases
Investigator
Investigator/Affiliation:
A Grabowska / ; M Herda / ; E Nikonorow / ; M J Schwaber / ; E Bilavsky / ; M Elenbogen / ; A Klein / ; S Navon-Venezia / ; M Shklyar / ; L Keren / ; R Glick / ; S Klarfeld-Lidji / ; E Mordechai / ; S Cohen / ; R Fachima / ; Y Zdonevsky / ; B Knubovets / ; J Lasley / ; I Bertucci / ; M-L Delaby / ; C Colmant / ; C Sacleux / ; R Formisano / ; M P Balice / ; E Guaglianone / ; S Camps / ; J Hart / ; E Isakov / ; A Friedman / ; A Rachman / ; G Franco / ; I Or / ; A Rabinovich /
Comments/Corrections

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