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Comparative placental morphology and function.
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MedLine Citation:
PMID:  829489     Owner:  NLM     Status:  MEDLINE    
The distinction between histiotrophic nutrition (in which local macromolecules are chiefly responsible for the maintenance of the embryo) and hemotrophic nutrition (which results from a transfer of material between the maternal and fetal circulations) is made. Placentation in a number of commonly used laboratory animals and in man is described, and it is shown that dependence upon histiotroph and hemotroph varies greatly, not only between species but also at different stages of gestation in a single species. These facts are likely to be reflected in considerably differences in response to certain teratogens; they must be carefully considered when experimental results are extrapolated between species. The significance to man of an agent which has been shown to be teratogenic in a single species of experimental animals should be evaluated in terms of possible differences in placental function between man and that species. This is particularly so if there is a suspicion that the potential teratogen may affect the fetal membranes.
F Beck
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Environmental health perspectives     Volume:  18     ISSN:  0091-6765     ISO Abbreviation:  Environ. Health Perspect.     Publication Date:  1976 Dec 
Date Detail:
Created Date:  1977-11-25     Completed Date:  1977-11-25     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0330411     Medline TA:  Environ Health Perspect     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  5-12     Citation Subset:  IM    
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MeSH Terms
Embryo Implantation
Embryo, Mammalian / anatomy & histology,  physiology
Extraembryonic Membranes / anatomy & histology,  physiology
Maternal-Fetal Exchange
Nutritional Physiological Phenomena
Placenta / anatomy & histology,  physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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Journal Information
Journal ID (nlm-ta): Environ Health Perspect
ISSN: 0091-6765
Article Information
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Print publication date: Month: 12 Year: 1976
Volume: 18First Page: 5 Last Page: 12
ID: 1475303
PubMed Id: 829489

Comparative placental morphology and function.
F Beck

Article Categories:
  • Research Article

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