Document Detail

Comparative morphometric study of AgNORs in variants of ameloblastoma.
MedLine Citation:
PMID:  23248466     Owner:  NLM     Status:  PubMed-not-MEDLINE    
AIMS: To compare the area and number of AgNORs (silver stained nucleolar organizer regions) by morphometry between follicular and plexiform variants of ameloblastoma in order to analyze their cell proliferation rates.
MATERIALS AND METHODS: This retrospective study was carried out on 30 cases each of follicular and plexiform ameloblastoma. The sections were obtained and stained with silver staining technique to identify the nucleolar organizer regions. AgNORs were quantified using two parameters; manual tag for the number of AgNORs and area measurement using the image analyzer software, Image-Pro-Express.
RESULTS: Morphometric area measurements of AgNOR were significantly higher for Plexiform ameloblastoma (0.831μm(2)) than follicular ameloblastoma (0.528μm(2)). Enumeration of the number of AgNORs showed a significantly higher number of AgNOR for follicular ameloblastoma (1.71) than plexiform ameloblastoma (1.43). Among the groups studied, follicular ameloblastoma was more aggressive than plexiform ameloblastoma, as it showed smaller AgNOR area and higher AgNOR number.
CONCLUSION: The combination of counting the number and measuring the area of AgNOR dots showed a significant overall difference between AgNOR profiles of follicular and plexiform variants of ameloblastoma.
Vijay Kumar Jain; K Uma; N Soundarya; R Sangeetha; T Smitha
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of oral and maxillofacial pathology : JOMFP     Volume:  16     ISSN:  0973-029X     ISO Abbreviation:  J Oral Maxillofac Pathol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-12-18     Completed Date:  2012-12-19     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  101227995     Medline TA:  J Oral Maxillofac Pathol     Country:  India    
Other Details:
Languages:  eng     Pagination:  354-8     Citation Subset:  -    
Department of Oral and Maxillofacial Pathology, M.R. Ambedkar Dental College, Bangalore, India.
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