| Comparative kinetics of phenobarbital after administration of the acid and the propylhexedrine salt (barbexaclone). | |
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MedLine Citation:
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PMID: 3709618 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The kinetics of phenobarbital (PB) was compared after oral administration of equivalent doses of the drug as the acid or the propylhexedrine salt (barbexaclone) to 7 normal volunteers. The absorption and elimination parameters were very similar. It was concluded that propylhexedrine did not affect the serum kinetics of PB given as barbexaclone. |
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Authors:
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E Perucca; R Grimaldi; G Ruberto; C Gelmi; F Trimarchi; A Crema |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: European journal of clinical pharmacology Volume: 29 ISSN: 0031-6970 ISO Abbreviation: Eur. J. Clin. Pharmacol. Publication Date: 1986 |
Date Detail:
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Created Date: 1986-07-24 Completed Date: 1986-07-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1256165 Medline TA: Eur J Clin Pharmacol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 729-30 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Half-Life Humans Kinetics Male Phenobarbital / analogs & derivatives*, blood, metabolism* |
| Chemical | |
Reg. No./Substance:
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4388-82-3/barbexaclone; 50-06-6/Phenobarbital |
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