Document Detail


Comparative in vitro study of bileaflet and tilting disk valve behavior in the pulmonary position.
MedLine Citation:
PMID:  16813455     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A study of mechanical heart valve behavior in the pulmonary position as a function of pulmonary vascular resistance is reported for the St. Jude Medical bileaflet (SJMB) valve and the MedicalCV Omnicarbon (OTD) tilting disk valve. Tests were conducted in a pulmonic mock circulatory system and impedance was varied in terms of system pulmonary vascular resistance (PVR). An impedance spectrum was found using instantaneous pulmonary artery pressure and flow rate curves. Both valves fully opened and closed at and above a nominal PVR of 3.0 mmHg/L/min. The SJMB valve was prone to leaflet bounce at closure, but otherwise completely closed, at settings above and below this nominal setting. At PVR values at and below 2.0 mmHg/L/min, the SJMB valve exhibited two types of leaflet aberrant behavior: single leaflet only closure while the other leaflet fluttered, and incomplete closure where both leaflets flutter but neither remain fully closed. The OTD valve fully opened and closed to a PVR value of 1.6 mmHg/L/min. At lower values, the valve did not close. Valves designed for the left heart can show aberrant behavior under normal conditions as pulmonary valves.
Authors:
Jeffrey Gohean; Richard Figliola; Tiffany Camp; Tim McQuinn
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of biomechanical engineering     Volume:  128     ISSN:  0148-0731     ISO Abbreviation:  J Biomech Eng     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-03     Completed Date:  2006-09-12     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7909584     Medline TA:  J Biomech Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  631-5     Citation Subset:  IM    
Affiliation:
Department of Mechanical Engineering and Bioengineering, Clemson University, Clemson, SC 29634-0921, USA.
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MeSH Terms
Descriptor/Qualifier:
Blood Flow Velocity
Blood Pressure
Equipment Failure Analysis*
Heart Valve Prosthesis*
Humans
Prosthesis Design
Pulmonary Artery / physiopathology*
Pulmonary Valve / physiopathology*,  surgery*
Treatment Outcome
Grant Support
ID/Acronym/Agency:
R01HL/HD67135-01/HD/NICHD NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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