Document Detail

Comparative hemodynamic effect of metrizamide and Renografin 76 in infants with congenital heart disease.
MedLine Citation:
PMID:  6344596     Owner:  NLM     Status:  MEDLINE    
Twenty patients under the age of 2 years with suspected congenital heart disease received alternately Renografin 76 and metrizamide for angiocardiography. The dose was 2.0 ml/kg per injection for both contrast media into the left ventricle. Metrizamide induced slightly lesser change in heart rate, peak systolic pressure, and peak end-diastolic pressures. Serum osmolality, hematocrit, and serum electrolytes were affected equally by the contrast media. Metrizamide was well tolerated by the neonates with congenital heart disease and its radiopacity was adequate for diagnostic purposes. At the doses administered, metrizamide does not seem to have any great advantage over Renografin 76 for angiocardiography in infants with severe congenital heart disease.
H A Baltaxe; P Mooring; J Kugler; W Pinsky; W K Chu
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  140     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  1983 Jun 
Date Detail:
Created Date:  1983-07-15     Completed Date:  1983-07-15     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1097-101     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Pressure / drug effects
Child, Preschool
Clinical Trials as Topic
Diatrizoate / analogs & derivatives*,  pharmacology*
Diatrizoate Meglumine / pharmacology*
Drug Combinations / pharmacology
Electrolytes / blood
Heart Defects, Congenital / radiography*
Heart Rate / drug effects
Hemodynamics / drug effects*
Metrizamide / pharmacology*
Osmolar Concentration
Time Factors
Reg. No./Substance:
0/Drug Combinations; 0/Electrolytes; 117-96-4/Diatrizoate; 131-49-7/Diatrizoate Meglumine; 31112-62-6/Metrizamide; 8064-12-8/urovision

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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