Document Detail

Comparative hemodynamic consequences of inflation hold, PEEP, and interrupted PEEP: an experimental study in normal dogs.
MedLine Citation:
PMID:  1093495     Owner:  NLM     Status:  MEDLINE    
Cardiac output and airway, intrathoracic, arterial, pulmonary artery, left atrial, and central venous pressures were studied in 8 mongrel dogs. They were anesthetized and ventilated with (1) inflation hold of various duration, (2) continuous positive end-expiratory pressure and one breath off). The results indicate a minimal decrease in cardiac output (of approximately 5 per cent) with inflation hold. Diminished cardiac output was noted with increasing levels of continuous PEEP. The severity of the decrease in cardiac output wasproportional to the airway pressure. The higher levels (20 cm H2O) OF PEEP were associated with profound decreases. Utilization of a technique of interrupted PEEP substantially reduced the adverse hemodynamic effects in the dog.
K F MacDonnell; A A Lefemine; H S Moon; D J Donovan; R P Johnston
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  19     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1975 May 
Date Detail:
Created Date:  1975-07-18     Completed Date:  1975-07-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  552-60     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Pressure
Cardiac Output
Central Venous Pressure
Intermittent Positive-Pressure Breathing*
Positive-Pressure Respiration* / instrumentation,  methods*
Pulmonary Artery / physiology
Respiration, Artificial / methods*
Vascular Resistance

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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