Document Detail

Comparative evaluation of piperacillin in vitro.
MedLine Citation:
PMID:  253573     Owner:  NLM     Status:  MEDLINE    
The minimal inhibitory concentrations of piperacillin and seven other betalactam antibiotics were determined against 407 bacterial isolates. Piperacillin was found to be more active than ampicillin against susceptible gram-negative bacilli and more active than either carbenicillin or ticarcillin against Pseudomonas aeruginosa and streptococci. Although piperacillin was active against Klebsiella pneumoniae, this activity was less than that of the cephalosporins. Piperacillin was not active against penicillin-resistant Staphylococcus aureus and Enterobacteriaceae that were resistant to the other test antibiotics.
G M Dickinson; T J Cleary; T A Hoffman
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Antimicrobial agents and chemotherapy     Volume:  14     ISSN:  0066-4804     ISO Abbreviation:  Antimicrob. Agents Chemother.     Publication Date:  1978 Dec 
Date Detail:
Created Date:  1979-04-25     Completed Date:  1979-04-25     Revised Date:  2010-09-02    
Medline Journal Info:
Nlm Unique ID:  0315061     Medline TA:  Antimicrob Agents Chemother     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  919-21     Citation Subset:  IM    
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MeSH Terms
Bacteria / drug effects*
Drug Evaluation
Penicillin Resistance
Penicillins / pharmacology*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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