Document Detail


Comparative evaluation of dopamine infusion & treadmill exercise tests in the diagnosis of coronary artery disease.
MedLine Citation:
PMID:  8119754     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dopamine infusion test (DIT) was compared with treadmill exercise test (TMT) in 20 patients of chronic stable angina (TMT +ve) for inducing reversible myocardial ischaemia so as to assess its efficacy as an alternative to TMT in patients who cannot perform exercise test due to certain non-cardiac diseases. DIT was positive in 15 of the 20 patients studied; five patients in whom DIT was negative had late onset, early offset changes in TMT. Haemodynamically the increase in heart rate (HR) was less but rise in systolic blood pressure (SBP) was more with dopamine infusion in comparison to the corresponding stage of TMT. However, evidence of myocardial ischaemia (ST segment depression) appeared at a lower rate pressure product (RPP) with dopamine infusion compared to exercise test. The test was tolerated well, in higher doses (stages III & IV) side effects like ventricular ectopic beats, palpitation and angina not warranting stoppage of test, were seen in some patients. Dopamine infusion is a good chemical stress test, and can be used as an alternative to TMT especially in situations where the latter cannot be performed. The test is simple, cost effective, non-invasive and well tolerated.
Authors:
S B Siwach; D Sharma; A Dua
Related Documents :
19804144 - Ranolazine, a new antianginal drug.
22446154 - Exercise adherence to pelvic floor muscle strengthening is not a significant predictor ...
8440584 - Effect of diltiazem on lid tension during light-flash-induced eye blinks in the rabbit.
3894474 - A dose-ranging, placebo-controlled, double-blind trial of nisoldipine in effort angina:...
24869994 - Exploring the link between standard lifestyle questionnaires administered during specif...
8467334 - The effect of isokinetic exercise on the relationship between blood lactate and muscle ...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Indian journal of medical research     Volume:  98     ISSN:  0971-5916     ISO Abbreviation:  Indian J. Med. Res.     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1994-04-05     Completed Date:  1994-04-05     Revised Date:  2013-04-18    
Medline Journal Info:
Nlm Unique ID:  0374701     Medline TA:  Indian J Med Res     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  213-7     Citation Subset:  IM    
Affiliation:
Postgraduate Department of Medicine, Medical College, Rohtak.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Angina Pectoris / diagnosis*,  physiopathology
Chronic Disease
Dopamine / administration & dosage,  diagnostic use*
Exercise Test*
Hemodynamics
Humans
Infusions, Intravenous
Male
Predictive Value of Tests

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A two-stage clinical trial of Phyllanthus amarus in hepatitis B carriers: failure to eradicate the s...
Next Document:  Effect of halothane exposure on motor skills & memory in anaesthetists.