Document Detail

Comparative evaluation of Glasgow Coma Score and gag reflex in predicting aspiration pneumonitis in acute poisoning.
MedLine Citation:
PMID:  19327309     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The purpose of the study was to assess the incidence of aspiration pneumonitis (AP) and its association with gag reflex and Glasgow Coma Score (GCS). MATERIALS AND METHODS: In a retrospective analysis study after prospective data collection, 155 poisoned patients with GCS less than or equal to 12 were evaluated. An assessment of GCS and the quality of gag reflex was made on arrival and recorded. Intubation status before gastrointestinal decontamination was noted. All patients were subsequently followed for developing of AP. RESULTS: The incidence of AP was 15.5%, with significant variance among patients with respect to the gag reflex, GCS, and the performance of intubation. A logistic regression model for predicting AP contained the following predictors: GCS (odds ratio [OR], 0.43; 95% confidence interval [CI], 0.30-0.62), intubation (OR, 0.07; 95% CI, 0.01-0.49), organophosphate ingestion (OR, 1.39; 95% CI, 0.96-2.01), and gastric evacuation (OR, 4.29; 95% CI, 0.94-9.51). In patients with reduced gag reflex, variations in GCS were associated with AP (OR, 0.43; 95% CI, 0.20-0.90), whereas in patients with absent gag reflex, age was the most important predictor of AP (OR, 2.67; 95% CI, 0.99-7.22). CONCLUSIONS: A reduced GCS and a nonintubated trachea are associated with an increased incidence of AP.
Nastaran Eizadi-Mood; Mahmood Saghaei; Sam Alfred; Amir Hooshang Zargarzadeh; Chanh Huynh; Farzad Gheshlaghi; Ahmad Yaraghi; Yousef Shadi Saad
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-01-17
Journal Detail:
Title:  Journal of critical care     Volume:  24     ISSN:  1557-8615     ISO Abbreviation:  J Crit Care     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-11     Completed Date:  2009-12-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8610642     Medline TA:  J Crit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  470.e9-15     Citation Subset:  IM    
Isfahan University of Medical Sciences, Isfahan, Iran.
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MeSH Terms
Glasgow Coma Scale*
Intubation, Gastrointestinal
Middle Aged
Pneumonia, Aspiration / diagnosis*,  etiology
Poisoning / complications,  physiopathology*
Retrospective Studies

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