Document Detail


Comparative efficacy of enrofloxacin, oxytetracycline, and sulfadimethoxine for the control of morbidity and mortality caused by Escherichia coli in broiler chickens.
MedLine Citation:
PMID:  15529991     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of the present study was to compare the ability of enrofloxacin, oxytetracycline, and sulfadimethoxine to reduce morbidity and mortality caused by Escherichia coli (colibacillosis) in broiler chickens. The chickens were raised in 80 pens (20 birds per pen) with 20 pens representing each treatment group under simulated commercial conditions that produced a colibacillosis challenge scenario. Each group of 20 randomized pens (replicates) was given one of four water treatments. Chickens that received enrofloxacin had significantly less mortality (P < 0.01), lower average gross pathology (colibacillosis) scores (P < 0.01), and better feed-conversion ratios (P < 0.05) than did chickens that received either oxytetracycline or no medication. Chickens that received enrofloxacin had significantly less mortality and lower pathology scores than those that received sulfadimethoxine and numerically lower feed conversion than the sulfadimethoxine group. Results from the present study show that enrofloxacin is superior to oxytetracycline and sulfadimethoxine for the control of morbidity and mortality caused by E. coli in broiler chickens. Our findings will help veterinarians choose and prescribe the most efficacious antimicrobial when treating colibacillosis.
Authors:
John R Glisson; Charles L Hofacre; Greg F Mathis
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Avian diseases     Volume:  48     ISSN:  0005-2086     ISO Abbreviation:  Avian Dis.     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-11-08     Completed Date:  2005-01-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370617     Medline TA:  Avian Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  658-62     Citation Subset:  IM    
Affiliation:
Department of Avian Medicine, The University of Georgia, Athens, GA 30602, USA.
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MeSH Terms
Descriptor/Qualifier:
Air Sacs / microbiology
Analysis of Variance
Animals
Anti-Bacterial Agents / therapeutic use*
Body Weight
Chickens / microbiology*
Escherichia coli Infections / drug therapy,  mortality,  pathology,  veterinary*
Fluoroquinolones / therapeutic use
Oxytetracycline / therapeutic use
Poultry Diseases / drug therapy*,  microbiology*,  mortality,  pathology
Quinolones / therapeutic use
Sulfadimethoxine / therapeutic use
Treatment Outcome
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Fluoroquinolones; 0/Quinolones; 122-11-2/Sulfadimethoxine; 79-57-2/Oxytetracycline; 93106-60-6/enrofloxacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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