Document Detail

Comparative effects of bicarbonate and dichloroacetate in newborn swine with hypoxic lactic acidosis.
MedLine Citation:
PMID:  1964114     Owner:  NLM     Status:  MEDLINE    
CONCLUSION: BC is a more effective alkalizer than DCA, which induced a greater renal vasodilation; both restored contractility.
D B Nudel; B J Peterson; B J Buckley; N A Kaplan; E Weinhaouse; N Gootman
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Developmental pharmacology and therapeutics     Volume:  15     ISSN:  0379-8305     ISO Abbreviation:  Dev Pharmacol Ther     Publication Date:  1990  
Date Detail:
Created Date:  1991-05-02     Completed Date:  1991-05-02     Revised Date:  2014-07-29    
Medline Journal Info:
Nlm Unique ID:  8003947     Medline TA:  Dev Pharmacol Ther     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  86-93     Citation Subset:  IM    
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MeSH Terms
Acidosis, Lactic / drug therapy*
Animals, Newborn
Bicarbonates / therapeutic use*
Blood Pressure / drug effects
Cardiac Output / drug effects
Dichloroacetic Acid / therapeutic use*
Heart Rate / drug effects
Hydrogen-Ion Concentration
Lactates / blood
Lactic Acid
Pulmonary Gas Exchange / drug effects
Sodium / therapeutic use*
Sodium Bicarbonate
Reg. No./Substance:
0/Bicarbonates; 0/Lactates; 33X04XA5AT/Lactic Acid; 8MDF5V39QO/Sodium Bicarbonate; 9LSH52S3LQ/Dichloroacetic Acid; 9NEZ333N27/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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