| Comparative effectiveness of radial probe endobronchial ultrasound versus CT-guided needle biopsy for evaluation of peripheral pulmonary lesions: A randomized pragmatic trial. | |
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MedLine Citation:
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PMID: 21875783 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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In many patients the optimal method of investigation of peripheral pulmonary lesions (PPL) is not clear. We performed a prospective randomized pragmatic trial to determine the comparative effectiveness of endobronchial ultrasound-guided transbronchial lung biopsy (EBUS-TBLB) and CT-guided percutaneous needle biopsy (CT-PNB) for the investigation of PPL. Overall complication rates were higher in those undergoing CT-PNB (27% v 3%, p = 0.03), while diagnostic accuracy of EBUS-TBLB was shown to be non-inferior to that of CT-PNB. Expected diagnostic accuracy and complication rates are likely to differ for individual patients on the basis of specific complex clinicoradiologic factors, which will influence the cost-benefit analysis between EBUS-TBLB and CT-PNB for individual patients. Further studies are required to examine the effect of these factors on clinical decision-making. |
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Authors:
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Daniel P Steinfort; Janette Vincent; Stefan Heinze; Phillip Antippa; Louis B Irving |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-8-27 |
Journal Detail:
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Title: Respiratory medicine Volume: - ISSN: 1532-3064 ISO Abbreviation: - Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-8-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8908438 Medline TA: Respir Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Crown Copyright © 2011. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Respiratory Medicine, Royal Melbourne Hospital, Parkville 3050, Australia; Department of Medicine (RMH/WH), University of Melbourne, Parkville 3010, Australia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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