Document Detail

Comparative effectiveness of advanced wound dressings for patients with chronic venous leg ulcers: A systematic review.
MedLine Citation:
PMID:  24635169     Owner:  NLM     Status:  In-Data-Review    
The purpose of this study was to systematically review the literature on the benefits and harms of advanced wound dressings on wound healing, mortality, quality of life, pain, condition of the wound bed, and adverse events for patients with chronic venous leg ulcers as compared with treatment with compression alone. We searched for primary studies in the databases of MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, and the Cumulative Index to Nursing and Allied Health Literature(®) from January 1980 through July 2012. Each study title, abstract, and full article was evaluated by two independent reviewers. Thirty-seven studies met our specific search criteria, although most evidence was of low or insufficient quality. Cellular dressings, collagen, and some antimicrobial dressings may improve healing rates of chronic venous leg ulcers vs. compression alone or other dressings. Limited data were available on other outcomes. The poor quality of the literature limits conclusions and necessitates future, well-conducted studies to evaluate the effectiveness of advanced wound dressings on chronic venous ulcers.
M Frances Valle; Nisa M Maruthur; Lisa M Wilson; Mahmoud Malas; Umair Qazi; Elisabeth Haberl; Eric B Bass; Jonathan Zenilman; Gerald Lazarus
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society     Volume:  22     ISSN:  1524-475X     ISO Abbreviation:  Wound Repair Regen     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-03-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9310939     Medline TA:  Wound Repair Regen     Country:  United States    
Other Details:
Languages:  eng     Pagination:  193-204     Citation Subset:  IM    
Copyright Information:
© 2014 by the Wound Healing Society.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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