Document Detail

Comparative diagnostic value of ankle-to-brachial index and transcutaneous oxygen tension at rest and after exercise in patients with intermittent claudication.
MedLine Citation:
PMID:  7702195     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Few studies have compared sensitivities of ankle-to-brachial index (ABI) and transcutaneous oxygen tension (TcPO2) in a large group of patients with Leriche stage II intermittent claudication. METHOD AND RESULTS: 111 patients (138 limbs) with a stable chronic (> three months) intermittent claudication and significant peripheral vascular disease (PVD) proved by angiography were studied. They performed a treadmill test (10%, 3 km/hr) limited by limb pain. ABI and TcPO2 were measured before, just after exercise, and after three and ten minutes of recovery in supine position. Sensitivities per patient for ABI and TcPO2 were respectively at rest: 82.9% and 28.8%, and after exercise: 88.3% and 62.2%. Sensitivities per leg (n = 138) for ABI and TcPO2 were respectively at rest: 73.9% and 26.8%, and after exercise: 82.6% and 34%. The sensitivity of TcPO2 increased to 56.5% after three minutes of recovery but was always less than that of ABI, which was maximal just after exercise (82.6%). The sensitivity of the regional perfusion index was similar to that of TcPO2. The sensitivity of TcPO2 increased with respect to the Leriche stage and the number of lesions but was always lower than that of ABI. There was a weak correlation between TcPO2 and ABI after exercise, but no correlation was noted between maximal walking distance, ABI, and TcPO2. CONCLUSION: TcPO2 is not required in patients with Leriche stage II intermittent claudication but might be useful either in severely affected patients (Leriche stage III or IV) or in selected patients.
P de Groote; A Millaire; G Deklunder; P Marache; E Decoulx; G Ducloux
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Angiology     Volume:  46     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-05-03     Completed Date:  1995-05-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  115-22     Citation Subset:  IM    
Department of Cardiology C, Cardiology Hospital, University of Lille, France.
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MeSH Terms
Analysis of Variance
Blood Gas Monitoring, Transcutaneous / statistics & numerical data
Blood Pressure*
Brachial Artery
Chronic Disease
Exercise / physiology*
Intermittent Claudication / blood,  diagnosis*,  physiopathology
Middle Aged
Oxygen / blood*
Rest / physiology*
Sensitivity and Specificity
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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