Document Detail


Comparative diagnostic value of ankle-to-brachial index and transcutaneous oxygen tension at rest and after exercise in patients with intermittent claudication.
MedLine Citation:
PMID:  7702195     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Few studies have compared sensitivities of ankle-to-brachial index (ABI) and transcutaneous oxygen tension (TcPO2) in a large group of patients with Leriche stage II intermittent claudication. METHOD AND RESULTS: 111 patients (138 limbs) with a stable chronic (> three months) intermittent claudication and significant peripheral vascular disease (PVD) proved by angiography were studied. They performed a treadmill test (10%, 3 km/hr) limited by limb pain. ABI and TcPO2 were measured before, just after exercise, and after three and ten minutes of recovery in supine position. Sensitivities per patient for ABI and TcPO2 were respectively at rest: 82.9% and 28.8%, and after exercise: 88.3% and 62.2%. Sensitivities per leg (n = 138) for ABI and TcPO2 were respectively at rest: 73.9% and 26.8%, and after exercise: 82.6% and 34%. The sensitivity of TcPO2 increased to 56.5% after three minutes of recovery but was always less than that of ABI, which was maximal just after exercise (82.6%). The sensitivity of the regional perfusion index was similar to that of TcPO2. The sensitivity of TcPO2 increased with respect to the Leriche stage and the number of lesions but was always lower than that of ABI. There was a weak correlation between TcPO2 and ABI after exercise, but no correlation was noted between maximal walking distance, ABI, and TcPO2. CONCLUSION: TcPO2 is not required in patients with Leriche stage II intermittent claudication but might be useful either in severely affected patients (Leriche stage III or IV) or in selected patients.
Authors:
P de Groote; A Millaire; G Deklunder; P Marache; E Decoulx; G Ducloux
Related Documents :
17174195 - The novel phosphodiesterase inhibitor nm-702 improves claudication-limited exercise per...
17063165 - Established and evolving medical therapies for claudication in patients with peripheral...
12499495 - [(123)i]-fp-cit-spect in the early diagnosis of pd presenting as exercise-induced dysto...
16711275 - Response of temporomandibular joint intermittent closed lock to different treatment mod...
20135145 - Effects of wind and rain on thermal responses of humans in a mildly cold environment.
8050035 - Cardiovascular effects of nacl microinjections into the nucleus of the solitary tract.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Angiology     Volume:  46     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-05-03     Completed Date:  1995-05-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  115-22     Citation Subset:  IM    
Affiliation:
Department of Cardiology C, Cardiology Hospital, University of Lille, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Analysis of Variance
Ankle
Blood Gas Monitoring, Transcutaneous / statistics & numerical data
Blood Pressure*
Brachial Artery
Chronic Disease
Exercise / physiology*
Female
Humans
Intermittent Claudication / blood,  diagnosis*,  physiopathology
Male
Middle Aged
Oxygen / blood*
Rest / physiology*
Sensitivity and Specificity
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Seeding of vascular grafts with an immortalized human dermal microvascular endothelial cell line.
Next Document:  Transesophageal echocardiography in evaluation of atrial masses.