| Comparative cardiovascular effects of drugs used for hypertension. | |
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MedLine Citation:
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PMID: 1968375 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Currently 4 classes of antihypertensive drugs - diuretics, beta-blockers, calcium channel blockers and angiotensin-converting enzyme (ACE) inhibitors - are most commonly used to treat hypertensive patients. Each class of drug has a distinctive cardiovascular pharmacodynamic profile and even within classes there exist agents with slightly different properties. The effects of the various drug classes on the heart and peripheral circulation, on the kidney and electrolyte metabolism, on the brain and on the renin-angiotensin system are now reasonably well described. Knowledge and understanding of these different cardiovascular effects are extremely important in order to adapt treatment to the needs of an individual patient. Furthermore, when combination therapy becomes necessary, the different cardiovascular aspects of the various drugs can be used to enhance antihypertensive efficacy and to attenuate adverse effects of separate compounds. |
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Authors:
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M Burnier; B Waeber; J Nussberger; H R Brunner |
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Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: Drugs Volume: 39 Suppl 1 ISSN: 0012-6667 ISO Abbreviation: Drugs Publication Date: 1990 |
Date Detail:
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Created Date: 1990-04-12 Completed Date: 1990-04-12 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7600076 Medline TA: Drugs Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 32-8 Citation Subset: IM |
Affiliation:
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Hypertension Division, University Hospital, Lausanne, Switzerland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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pharmacology Angiotensin-Converting Enzyme Inhibitors / pharmacology Antihypertensive Agents / pharmacology* Calcium Channel Blockers / pharmacology Cardiovascular System / drug effects* Diuretics / pharmacology Humans |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Antihypertensive Agents; 0/Calcium Channel Blockers; 0/Diuretics |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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