Document Detail


Comparative bioavailability study of acetaminophen solutions used in hospital formulary.
MedLine Citation:
PMID:  8364517     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To learn the influence of polyethylene glycol (PEG) on bioavailability, this study compared the bioavailability of acetaminophen in the presence of 10% ethanol (acetaminophen-ethanol liquid) to that in the presence of 10% PEG (acetaminophen-PEG liquid) since these two preparations are commonly used in hospital formulary. The results in Thai male volunteers showed there was not significantly different.
Authors:
S Prakongpan; R Puncoke; T Nagai
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Biological & pharmaceutical bulletin     Volume:  16     ISSN:  0918-6158     ISO Abbreviation:  Biol. Pharm. Bull.     Publication Date:  1993 Jun 
Date Detail:
Created Date:  1993-10-04     Completed Date:  1993-10-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9311984     Medline TA:  Biol Pharm Bull     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  613-5     Citation Subset:  IM    
Affiliation:
Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
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MeSH Terms
Descriptor/Qualifier:
Acetaminophen / administration & dosage,  pharmacokinetics*
Adolescent
Adult
Biological Availability
Chromatography, High Pressure Liquid
Ethanol
Formularies, Hospital*
Humans
Male
Polyethylene Glycols
Solutions
Spectrophotometry, Ultraviolet
Chemical
Reg. No./Substance:
0/Polyethylene Glycols; 0/Solutions; 103-90-2/Acetaminophen; 64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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