Document Detail


Comparative analysis of soft neurological signs in positive and negative subtype of schizophrenia.
MedLine Citation:
PMID:  19556945     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The objective of the study was to investigate neurological deficit in schizophrenia and to compare soft neurological signs in positive and negative subtypes of schizophrenia. SUBJECTS AND METHODS: 66 patients with schizophrenia were evaluated with the Positive and Negative Syndrome Scale to classify the subtype of schizophrenia: positive subtype (36 patients) and negative subtype (30 patients), all of which were entering into remission. To examine the neurological soft signs we compared scores on the Neurological Evaluation Scale (NES) for positive and negative subtype. RESULTS: The negative subtype of schizophrenia showed significantly higher neurological soft signs in comparison to the positive subtype, with reduced functioning in the sensory integration and motor coordination subscale as well as the other subscale. CONCLUSION: The main finding in this study indicates that patients with schizophrenia have neurological impairment, and that the negative subtype has significantly higher neurological impairment than the positive subtype. The results further support the significance of the soft neurological signs as a possible marker of different subtypes of schizophrenia.
Authors:
Tijana Cvetić; Olivera Vuković; Dubravka Britvić; Maja Ivković; Slavica Dukić-Dejanović; Dusica Lecić-Tosevski
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Psychiatria Danubina     Volume:  21     ISSN:  0353-5053     ISO Abbreviation:  Psychiatr Danub     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-26     Completed Date:  2009-08-21     Revised Date:  2009-10-20    
Medline Journal Info:
Nlm Unique ID:  9424753     Medline TA:  Psychiatr Danub     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  174-8     Citation Subset:  IM    
Affiliation:
Institute of Psychiatry Clinical Center of Serbia, Pasterova 2, 11000 Belgrade, Serbia. tijanacvetic@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Humans
Male
Nervous System Diseases / diagnosis*,  psychology
Neurologic Examination / statistics & numerical data*
Psychiatric Status Rating Scales / statistics & numerical data*
Psychometrics
Schizophrenia / classification,  diagnosis*
Schizophrenic Psychology*
Young Adult
Comments/Corrections
Comment In:
Psychiatr Danub. 2009 Sep;21(3):327-8   [PMID:  19794349 ]

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