| Comparative analysis of gene expression profiles in ruminal tissue from Holstein dairy cows fed high or low concentrate diets. | |
| | |
MedLine Citation:
|
PMID: 20732839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cattle are often fed high concentrate (HC) diets to increase productivity, although HC diets cause changes in ruminal environment such as pH reduction. Despite those well-documented changes in cattle fed HC diets, there is currently a paucity of data describing the molecular events regulating the ruminal environment. Our objective was to gain an understanding of which genes are differentially expressed in ruminal tissue from Holstein cows fed a HC comparing to low concentrate (LC) diet using microarray analysis using a bovine 24 k microarray. A total of 5,200 differentially expressed genes (DEG) were detected for cows fed HC relative to LC. The DEG were firstly annotated with gene ontology (GO) and Kyoto encyclopedia of Genes and Genomes (KEGG), indicating that the DEG were associated with catalytic activity and MAPK pathway, respectively. Further characterization using GeneCodis identified patterns of interrelated annotations for the DEG to elucidate the relationships among annotation groups revealed that a cAMP-dependent protein kinase A catalytic subunit beta (PRKACB), may be associated with ruminal tissue maintenance. The results contributed to understanding of the regulatory mechanisms at the mRNA level for Holstein cows fed at different concentrate ratio diets. |
| | |
Authors:
|
Masaaki Taniguchi; Gregory B Penner; Karen A Beauchemin; Masahito Oba; Le Luo Guan |
Related Documents
:
|
9087929 - In vivo indicators of pathologic ruminal sulfide production in steers with diet-induced... 3571009 - Effects of potassium on macromineral absorption in sheep fed wheat straw-based diets. 8385089 - Influence of aspergillus oryzae fermentation extract on forage intake, site of digestio... 10438039 - Effects of level of feeding and ruminally undegraded protein on ruminal bacterial prote... 2170319 - Differential passage rates and digestion of neutral detergent fiber from grain and fora... 1452849 - In vivo degradation of protein in diets formulated for two degradabilities. 9683389 - A comparison of the effect of free access to reduced fat products or their full fat equ... 8529319 - Novel low-dosage hormonal replacement therapy complements dietary treatment of moderate... 19389969 - Crushed sunflower, flax, or canola seeds in lactating dairy cow diets: effects on metha... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-08-02 |
Journal Detail:
|
Title: Comparative biochemistry and physiology. Part D, Genomics & proteomics Volume: 5 ISSN: 1878-0407 ISO Abbreviation: Comp. Biochem. Physiol. Part D Genomics Proteomics Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2010-12-06 Completed Date: 2011-03-29 Revised Date: 2011-04-19 |
Medline Journal Info:
|
Nlm Unique ID: 101270611 Medline TA: Comp Biochem Physiol Part D Genomics Proteomics Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 274-9 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Cattle / metabolism* Cyclic AMP-Dependent Protein Kinases / analysis, metabolism Diet / veterinary* Female Gene Expression Profiling* Microarray Analysis / veterinary Rumen / chemistry, metabolism* |
| Chemical | |
Reg. No./Substance:
|
EC 2.7.11.11/Cyclic AMP-Dependent Protein Kinases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Why does the Great Chinese Famine affect the male and female survivors differently? Mortality select...
Next Document: Strong intra- and inter-continental differentiation revealed by Y chromosome SNPs M269, U106 and U15...