Document Detail

Comparative analysis of the anxiety-related behaviors in four inbred mice.
MedLine Citation:
PMID:  12426069     Owner:  NLM     Status:  Publisher    
An anxiety-related behavior is an emotional response of an organism, which is quantitatively measured by several behavioral paradigms. We employed two most frequently used behavioral tests, the open field and light-dark exploration, to comparatively analyze the anxiety-like behaviors in four inbred mice. For an accurate recording of movement, motion analysis software was developed that acquires a real-time video input to generate a behavioral path. Effects of the strains on the test results were evaluated by ANOVA with the Newman-Keuls post hoc comparison. Eight different behavioral indices, four from each tests, were grouped into two classes; the results of duration, center crossing, transition, rearing, and ambulation indicate strain differences of FVB/N>C57BL/6J>/=BALB/cA>/=CBA/N (I), while stretched-attend posture, peeping, and defecation show the tendency of FVB/N=C57BL/6J<CBA/N</=BALB/cA (II). The peeping is a novel type of behavior observed in this work. Although there is a variation among behavioral indices in their discrimination between inbred lines, the behaviors are highly correlated one another such that each class I or class II behaviors are clustered on two orthogonal factor planes as a result of the principal component analysis. The polarization of each inbred line toward these two behavioral biases may reflect genetic backgrounds of these strains.
Sanghyeon Kim; Sukchan Lee; Sungho Ryu; Jea gyun Suk; Chankyu Park
Related Documents :
16811789 - Temporal inhibition: effects of changes in rate of reinforcement and rate of responding.
16811569 - Intermittent reinforcement of an interresponse time.
16811529 - Response-dependent and response-independent timeout from an avoidance schedule.
16812649 - Discriminability between alternatives in a switching-key concurrent schedule.
21048229 - Concurrent vr vi schedules: primacy of molar control of preference and molecular contro...
20152889 - Extinction, relapse, and behavioral momentum.
20857489 - Effect of posterior tibial slope on knee biomechanics during functional activity.
11332519 - Paired-comparison hearing aid preferences: evaluation of an unforced-choice paradigm.
23124919 - Dynamic primitives of motor behavior.
Publication Detail:
Journal Detail:
Title:  Behavioural processes     Volume:  60     ISSN:  1872-8308     ISO Abbreviation:  Behav. Processes     Publication Date:  2002 Nov 
Date Detail:
Created Date:  2002-Nov-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703854     Medline TA:  Behav Processes     Country:  -    
Other Details:
Languages:  ENG     Pagination:  181-190     Citation Subset:  -    
National Creative Research Initiative Center for Behavioral Genetics, Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Yusong-Ku, 305-701, Taejon, Republic of Korea
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Emotions in farm animals: a new approach to animal welfare in applied ethology.
Next Document:  Synthesis and characterization of a dianionic carbohydrate-based phospholipid.