Document Detail


Comparative analysis of accumulation of chlorine e6 and hematoporphyrin derivatives in subpopulations of peripheral blood lymphocytes.
MedLine Citation:
PMID:  15662459     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied accumulation of porphyrin photosensitizers chlorine e6, hematoporphyrin, and their derivatives by different lymphocyte subpopulations. The intensity of staining of B lymphocytes and natural killer cells with photosensitizers was higher compared to T lymphocytes. T cell subpopulation differed by their ability to bind photosensitizers. Relative accumulation of dimethyl esters of chlorine e6 and hematoporphyrin in cells surpassed that of nonesterified porphyrins.
Authors:
V P Savitskii; V P Zorin; M P Potapnev; A Ya Potapenko
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  138     ISSN:  0007-4888     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2005-01-21     Completed Date:  2005-06-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  158-62     Citation Subset:  IM    
Affiliation:
Republican Research-and-Production Center for Child Oncology and Hematology, Minsk. savitskiy_v@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
B-Lymphocyte Subsets / metabolism
Hematoporphyrin Derivative / metabolism*
Hematoporphyrin Photoradiation
Humans
Lymphocyte Subsets / metabolism*
Porphyrins / metabolism*
T-Lymphocyte Subsets / metabolism
Chemical
Reg. No./Substance:
0/Porphyrins; 19660-77-6/chlorin e6; 68335-15-9/Hematoporphyrin Derivative

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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