| Comparative analysis of accumulation of chlorine e6 and hematoporphyrin derivatives in subpopulations of peripheral blood lymphocytes. | |
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MedLine Citation:
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PMID: 15662459 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied accumulation of porphyrin photosensitizers chlorine e6, hematoporphyrin, and their derivatives by different lymphocyte subpopulations. The intensity of staining of B lymphocytes and natural killer cells with photosensitizers was higher compared to T lymphocytes. T cell subpopulation differed by their ability to bind photosensitizers. Relative accumulation of dimethyl esters of chlorine e6 and hematoporphyrin in cells surpassed that of nonesterified porphyrins. |
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Authors:
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V P Savitskii; V P Zorin; M P Potapnev; A Ya Potapenko |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Bulletin of experimental biology and medicine Volume: 138 ISSN: 0007-4888 ISO Abbreviation: Bull. Exp. Biol. Med. Publication Date: 2004 Aug |
Date Detail:
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Created Date: 2005-01-21 Completed Date: 2005-06-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372557 Medline TA: Bull Exp Biol Med Country: United States |
Other Details:
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Languages: eng Pagination: 158-62 Citation Subset: IM |
Affiliation:
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Republican Research-and-Production Center for Child Oncology and Hematology, Minsk. savitskiy_v@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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B-Lymphocyte Subsets
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metabolism Hematoporphyrin Derivative / metabolism* Hematoporphyrin Photoradiation Humans Lymphocyte Subsets / metabolism* Porphyrins / metabolism* T-Lymphocyte Subsets / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Porphyrins; 19660-77-6/chlorin e6; 68335-15-9/Hematoporphyrin Derivative |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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