| A comparative study of perfusion measurement in brain tumours at 3 Tesla MR: Arterial spin labeling versus dynamic susceptibility contrast-enhanced MRI. | |
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MedLine Citation:
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PMID: 20558984 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To prove the feasibility of arterial spin labeling (ASL) to explore brain tumors by comparing dynamic susceptibility contrast-enhanced MRI to ASL at 3T MR. MATERIALS AND METHODS: Twenty-seven patients were included presenting 9 gliomas, 10 metastases and 8 meningiomas. All were explored by a pseudo-continuous ASL and dynamic susceptibility contrast-enhanced T2* perfusion sequence. Two neuroradiologists analyzed the cerebral blood flow (CBF) maps to assess feasibility, examination quality and quantitative comparison. The Spearman nonparametric correlation test and the Bland-Altman graphic test were used to analyze our quantitative results. RESULTS: 92% of ASL CBF maps were informative. ASL detected all lesions as well as dynamic susceptibility contrast-enhanced MRI. Both sequences provide relative quantitative CBF values closely correlated. CONCLUSION: On a 3T MR unit, ASL is a good alternative to dynamic susceptibility contrast-enhanced MRI when contrast medium is contraindicated or intravenous injection is not possible. Its results on relative CBF parameters are similar to contrast-injected perfusion. |
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Authors:
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P Lehmann; P Monet; G de Marco; G Saliou; M Perrin; S Stoquart-Elsankari; A Bruniau; J N Vallée |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2010-06-19 |
Journal Detail:
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Title: European neurology Volume: 64 ISSN: 1421-9913 ISO Abbreviation: Eur. Neurol. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-07-28 Completed Date: 2010-11-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0150760 Medline TA: Eur Neurol Country: Switzerland |
Other Details:
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Languages: eng Pagination: 21-6 Citation Subset: IM |
Copyright Information:
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2010 S. Karger AG, Basel. |
Affiliation:
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Neuroradiology, Amiens University Hospital, France. pierre.lehmann@ah-hm.fr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Arteries / pathology* Brain Neoplasms / diagnosis* Cerebrovascular Circulation / physiology Contrast Media / diagnostic use* Female Humans Image Processing, Computer-Assisted / methods Magnetic Resonance Imaging / methods* Male Middle Aged Perfusion / methods* Retrospective Studies Spin Labels* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Spin Labels |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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