Document Detail


Comparative study of different combinations of microvascular anastomoses in a rat model: end-to-end, end-to-side, and flow-through anastomosis.
MedLine Citation:
PMID:  18626360     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: This study aimed to compare several microvascular anastomotic techniques by patency rate using a free flap model in rats.
METHODS: A microsurgical transfer model of a pectoral skin flap to the cervical region was used. In experiment 1, 120 rats were divided into four groups (n = 30 in each group) depending on the type of microvascular anastomotic technique. For group 1, end-to-end anastomoses were performed for arteries and veins. For group 2, end-to-side anastomoses were performed for arteries and end-to-end anastomoses were performed for veins. For group 3, flow-through anastomoses were performed for arteries and end-to-end anastomoses were performed for veins. For group 4, end-to-end anastomoses were performed for arteries and end-to-side anastomoses were performed for veins. Flap survival was assessed on day 3 and the success rates of the four groups compared. In experiment 2 (n = 10), postoperative blood flows of end-to-end and flow-through arterial anastomoses were measured.
RESULTS: : In experiment 1, the success rates in groups 1, 2, 3, and 4 were 76.7, 83.3, 100, and 83.3 percent, respectively. Differences between group 3 and the other groups were statistically significant. In experiment 2, the blood flow of flow-through arterial anastomosis (1.8 ml/minute) was much higher than that of end-to-end anastomosis (0.18 ml/minute).
CONCLUSIONS: : Flow-through arterial anastomosis presented a higher blood flow through the anastomotic site, resulting in a higher success rate than conventional anastomoses. In veins, end-to-side anastomosis was equivalent to end-to-end anastomosis even though the diameter of the donor vein was larger than the recipient vein.
Authors:
Shimpei Miyamoto; Mutsumi Okazaki; Norihiko Ohura; Tomohiro Shiraishi; Akihiko Takushima; Kiyonori Harii
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Plastic and reconstructive surgery     Volume:  122     ISSN:  1529-4242     ISO Abbreviation:  Plast. Reconstr. Surg.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2010-07-27     Completed Date:  2010-08-16     Revised Date:  2011-02-16    
Medline Journal Info:
Nlm Unique ID:  1306050     Medline TA:  Plast Reconstr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  449-55     Citation Subset:  AIM; IM    
Affiliation:
Department of Plastic and Reconstructive Surgery, Kyorin University School of Medicine, Tokyo, Japan. shinpei@kyorin-u.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Anastomosis, Surgical / methods*
Animals
Blood Flow Velocity / physiology
Male
Microcirculation / physiology*
Microsurgery / methods*
Necrosis
Rats
Rats, Wistar
Surgical Flaps / blood supply*
Thrombosis / pathology
Vascular Patency / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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