Document Detail

Comparative Study on Antioxidant Activity of Lycopene (Z)-Isomers in Different Assays.
MedLine Citation:
PMID:  21476575     Owner:  NLM     Status:  Publisher    
Several studies have implicated the potent antioxidant properties of lycopene. However, most of the studies used only the (all-E)-isomer. (Z)-Isomers of lycopene were found in substantial amounts in processed foods and in human tissues. In the present study, we investigated in vitro the antioxidant activity of (5Z)-, (9Z)-, and (13Z)-lycopene compared to the (all-E)-isomer. Additionally, prolycopene, the (7Z,9Z,7'Z,9'Z)-isomer found in tangerine tomatoes, was analyzed. No significant differences were found between the isomers in ferric reducing antioxidant power assay and in bleaching the radical cation of 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), both based on ET mechanisms. In contrast, scavenging activity against peroxyl radicals generated by thermal degradation of 2,2'-azobis(2-amidinopropane) (AAPH) was higher in the (Z)-isomers. (5Z)-Lycopene was most antioxidant in scavenging lipid peroxyl radicals, evaluated by analyzing the inhibition of MbFe(III) lipid peroxidation of linoleic acid in mildly acidic conditions (pH 5.8) in a micellar environment, modeling a possible antioxidant action in the gastric compartment.
Lars Müller; Pascale Goupy; Kati Fröhlich; Olivier Dangles; Catherine Caris-Veyrat; Volker Böhm
Related Documents :
2914385 - Homogentisic acid determined in biological fluids by hplc.
2466505 - Direct concurrent measurement of urinary vanillylmandelic acid, 5-hydroxyindoleacetic a...
22020145 - N-3 polyunsaturated fatty acids exert immunomodulatory effects on lymphocytes by target...
2548975 - High specific activity 15-(p-[123i]iodophenyl)pentadecanoic acid.
11979985 - Introduction to an alternate view of acid/base balance: the strong ion difference or st...
11804395 - Topical anti-inflammatory activity of thymus willdenowii.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-8
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  -     ISSN:  1520-5118     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Institute of Nutrition, Friedrich Schiller University Jena , Dornburger Strasse 25-29, D-07743 Jena, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A Brief Synthesis of (-)-Englerin A.
Next Document:  Portable Surface Plasmon Resonance Immunosensor for the Detection of Fluoroquinolone Antibiotic Resi...