| Comparative effect of green tea, chokeberry and honeysuckle polyphenols on nutrients and mineral absorption and digestibility in rats. | |
| | |
MedLine Citation:
|
PMID: 20150725 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND/AIMS: Natural polyphenols are chemically and biologically active. This study aimed at examining the physiological effects of high doses of polyphenol extracts from green tea and new polyphenol-rich sources (chokeberry and honeysuckle fruits) on nutrient absorption. METHODS: 32 male Wistar rats were divided into four groups and fed a diet supplemented with one of the three polyphenolic extracts (at 0.4%) or a control diet for 4 weeks. A perfusion technique was used to study the effects at intestinal level. Pure polyphenols from the three sources were introduced into perfusion fluid at a concentration of 0.4% and allowed to cross the intestinal tract in 1.5 h. RESULTS: In the perfusion experiment, addition of the extracts caused a strong and statistically significant reduction in absorption of the selected nutrients (water, glucose, cholesterol, amino acids and minerals) compared to control animals. In the nutritional experiment, we recorded a slight decrease in diet utilization and growth in rats on polyphenolic diets relative to control group. In the same experiment, we observed a reduction of Zn and Cu absorption, but this was not accompanied by diminished concentrations in the bone femur. CONCLUSIONS: The presence of the polyphenolic extracts in the perfusion liquids significantly reduced absorption from the small intestine, but the nutritional experiment did not confirm deleterious consequences of the consumption of high extract doses. |
| | |
Authors:
|
Slawomir Frejnagel; Monika Wroblewska |
Related Documents
:
|
1910165 - Intestinal permeability, atopic eczema and oral disodium cromoglycate. 10075345 - Composition of enteral diets and meals providing optimal absorption rates of nutrients ... 6706215 - The ileal brake--inhibition of jejunal motility after ileal fat perfusion in man. 8395805 - Experimental infection of specific-pathogen-free turkey poults with single and combined... 8117745 - In vivo regulation of hepatic lipase activity and mrna levels by diets which modify cho... 7734785 - Placental supply of energy and protein substrates to the fetus. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-02-11 |
Journal Detail:
|
Title: Annals of nutrition & metabolism Volume: 56 ISSN: 1421-9697 ISO Abbreviation: Ann. Nutr. Metab. Publication Date: 2010 |
Date Detail:
|
Created Date: 2010-04-16 Completed Date: 2010-07-12 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8105511 Medline TA: Ann Nutr Metab Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 163-9 Citation Subset: IM |
Copyright Information:
|
(c) 2010 S. Karger AG, Basel. |
Affiliation:
|
Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland. slawus @ pan.olsztyn.pl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Bone and Bones / metabolism Caseins / pharmacology Diet Digestion* Feces / chemistry Flavonoids / pharmacology* Food* Intestinal Absorption / drug effects* Intestine, Small / drug effects, metabolism Lonicera / chemistry* Male Minerals / metabolism*, urine Nitrogen / metabolism, urine Perfusion Phenols / pharmacology* Photinia / chemistry* Rats Rats, Wistar Spectrophotometry, Atomic Tea / chemistry* |
| Chemical | |
Reg. No./Substance:
|
0/Caseins; 0/Flavonoids; 0/Minerals; 0/Phenols; 0/Tea; 0/polyphenols; 7727-37-9/Nitrogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Preferences for Hereditary Breast and Ovarian Cancer Information among Mexican, Cuban and Puerto Ric...
Next Document: Successful Treatment of Severe Hypertriglyceridemia with a Formula Diet Rich in Omega-3 Fatty Acids ...