Document Detail


A comparative analysis of PTFE-covered and uncovered stents for palliative treatment of malignant extrahepatic biliary obstruction.
MedLine Citation:
PMID:  21098180     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of our study was to evaluate the outcomes of the newly designed partially polytetrafluoroethylene (PTFE)-covered stent and compare the outcomes of PTFE-covered and uncovered stents in patients with malignant extrahepatic biliary obstruction.
MATERIALS AND METHODS: From March 2006 to December 2008, 58 consecutive patients who underwent PTFE-covered stent placement were prospectively studied. Those data were compared with data obtained by retrospectively studying 58 consecutive patients who underwent self-expanding uncovered stent placement from March 2003 to February 2006.
RESULTS: According to the Kaplan-Meier analysis, the cumulative stent patency of covered stents (98%, 98%, 91%, 76%, and 76% at 1, 3, 6, 9, and 12 months, respectively) was significantly better than that of uncovered stents (98%, 83%, 72%, 57%, and 57% at 1, 3, 6, 9, and 12 months, respectively) (p = 0.037). There was no significant difference in the patient survival between the groups (p = 0.479). The two groups also did not significantly differ in terms of complication rate (p = 0.717), with 8.6% (5/58) in the covered stent group and 5.2% (3/58) in the uncovered stent group.
CONCLUSION: Partially PTFE-covered stents are effective and safe for the palliative treatment of malignant extrahepatic biliary obstruction. Moreover, PTFE-covered stents were significantly superior to uncovered stents in terms of stent patency for palliative treatment of patients with malignant extrahepatic biliary obstruction. In addition, there was no significant difference in patient survival and complication rate between the PTFE-covered and uncovered stent group.
Authors:
Dong Il Gwon; Gi-Young Ko; Jin Hyoung Kim; Hyun-Ki Yoon; Im Sick Lee; Kyung-Ah Kim; Kyu-Bo Sung
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  195     ISSN:  1546-3141     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-24     Completed Date:  2011-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  W463-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86, Asanbyeongwon-gil, Songpa-gu, Seoul, 138-736 Korea. radgwon@amc.seoul.kr
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Bile Duct Neoplasms / therapy*
Cholestasis, Extrahepatic / therapy*
Coated Materials, Biocompatible
Equipment Design
Female
Humans
Male
Middle Aged
Palliative Care / methods*
Polytetrafluoroethylene
Prospective Studies
Retrospective Studies
Statistics, Nonparametric
Stents*
Survival Rate
Treatment Outcome
Chemical
Reg. No./Substance:
0/Coated Materials, Biocompatible; 9002-84-0/Polytetrafluoroethylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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