| A comparative analysis of PTFE-covered and uncovered stents for palliative treatment of malignant extrahepatic biliary obstruction. | |
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MedLine Citation:
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PMID: 21098180 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of our study was to evaluate the outcomes of the newly designed partially polytetrafluoroethylene (PTFE)-covered stent and compare the outcomes of PTFE-covered and uncovered stents in patients with malignant extrahepatic biliary obstruction. MATERIALS AND METHODS: From March 2006 to December 2008, 58 consecutive patients who underwent PTFE-covered stent placement were prospectively studied. Those data were compared with data obtained by retrospectively studying 58 consecutive patients who underwent self-expanding uncovered stent placement from March 2003 to February 2006. RESULTS: According to the Kaplan-Meier analysis, the cumulative stent patency of covered stents (98%, 98%, 91%, 76%, and 76% at 1, 3, 6, 9, and 12 months, respectively) was significantly better than that of uncovered stents (98%, 83%, 72%, 57%, and 57% at 1, 3, 6, 9, and 12 months, respectively) (p = 0.037). There was no significant difference in the patient survival between the groups (p = 0.479). The two groups also did not significantly differ in terms of complication rate (p = 0.717), with 8.6% (5/58) in the covered stent group and 5.2% (3/58) in the uncovered stent group. CONCLUSION: Partially PTFE-covered stents are effective and safe for the palliative treatment of malignant extrahepatic biliary obstruction. Moreover, PTFE-covered stents were significantly superior to uncovered stents in terms of stent patency for palliative treatment of patients with malignant extrahepatic biliary obstruction. In addition, there was no significant difference in patient survival and complication rate between the PTFE-covered and uncovered stent group. |
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Authors:
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Dong Il Gwon; Gi-Young Ko; Jin Hyoung Kim; Hyun-Ki Yoon; Im Sick Lee; Kyung-Ah Kim; Kyu-Bo Sung |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 195 ISSN: 1546-3141 ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-24 Completed Date: 2011-01-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: W463-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86, Asanbyeongwon-gil, Songpa-gu, Seoul, 138-736 Korea. radgwon@amc.seoul.kr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Bile Duct Neoplasms / therapy* Cholestasis, Extrahepatic / therapy* Coated Materials, Biocompatible Equipment Design Female Humans Male Middle Aged Palliative Care / methods* Polytetrafluoroethylene Prospective Studies Retrospective Studies Statistics, Nonparametric Stents* Survival Rate Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Coated Materials, Biocompatible; 9002-84-0/Polytetrafluoroethylene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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