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Comparative Analysis of Clinical Characteristics of Pandemic Influenza A/H1N1 and Seasonal Influenza A Infections in Hospitalized Children.
MedLine Citation:
PMID:  23190773     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Pandemic influenza A/H1N1 (piA) caused significant morbidity and mortality worldwide. We compared characteristics of piA (2009/10) to those of seasonal influenza A (siA; 2007/08/09) in 134 (piA/siA: N=55/79) hospitalized patients <18 years of age. Chronic disease was present in 25%/33%. Most common symptoms were fever (87%/94%), cough (78%/86%), rhinitis (76%/76%) and pharyngitis (67%/68%). Croup syndrome (15%/3%), conjunctivitis (31%/10%) and febrile seizures (26%/13%) were more frequent in piA; 64%/53% patients had >1 complication and 5 (3/2) were admitted to ICU. Oseltamivir use was 20%/0%. Severity of pandemic influenza disease was not different compared with seasonal influenza A in preceding years.
Authors:
Ulrich Heininger; Gurli Baer; Anna-Julia Ryser; Yulin Li
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-28
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  -     ISSN:  1532-0987     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Division of Pediatric Infectious Diseases, University Children's Hospital, University of Basel, Switzerland.
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