Document Detail

Comparability of neuropsychological test profiles in patients with chronic substance abuse and mild traumatic brain injury.
MedLine Citation:
PMID:  17853134     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to compare 104 patients with acute uncomplicated mild traumatic brain injury (MTBI) to a sample of 104 patients from an inpatient substance abuse program to determine whether these patients could be differentiated by their pattern of relative cognitive strengths and weaknesses. Patients were matched on age, education, and gender. Eight cognitive measures were used that included tests of attention, memory, and processing speed. There were no statistically significant differences between the two groups on any of the cognitive measures. Using a two-step cluster analysis procedure (i.e., hierarchical and k-means analyses), seven common profiles were identified. There was no significant difference in the proportions of patients from the MTBI or substance abuse group in each of the seven profiles. These results show that patients with uncomplicated MTBIs could not be reliably differentiated from patients with substance abuse problems on these cognitive measures. This is of particular concern for clinicians evaluating the neuropsychological effects of MTBI in individuals with a comorbid history of substance abuse.
Rael T Lange; Grant L Iverson; Michael D Franzen
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Clinical neuropsychologist     Volume:  22     ISSN:  1385-4046     ISO Abbreviation:  Clin Neuropsychol     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-07-01     Completed Date:  2008-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8806548     Medline TA:  Clin Neuropsychol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  209-27     Citation Subset:  IM    
British Columbia Mental Health and Addiction Services, Department of Research, Riverview Hospital, Coquitlam, British Columbia, Canada.
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MeSH Terms
Attention / physiology
Brain Injuries / physiopathology*,  psychology
Case-Control Studies
Cluster Analysis
Cognition Disorders / diagnosis,  etiology
Memory / physiology
Middle Aged
Multivariate Analysis
Neuropsychological Tests*
Substance-Related Disorders / physiopathology*,  psychology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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