| Comorbidity, multimorbidity and personalized psychosomatic medicine: epigenetics rolling on the horizon. | |
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MedLine Citation:
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PMID: 20562744 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This review focuses first on conceptual chaos and different connotations in psychosomatic medicine, then on new perspectives on comorbidity and multimorbidity, especially from epigenetics perspective. Comorbidity is one of the greatest research and clinical challenges to contemporary psychiatry and psychosomatic medicine. Recently altered gene expression due to epigenetic regulation has been implicated in the development of multifarious mental disorders and somatic diseases. The potential relevance of epigenetics for better understanding and more successful treatment of comorbidity and multimorbidity is described. |
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Authors:
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Miro Jakovljević; Zeljko Reiner; Davor Milicić; Zeljka Crncević |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Psychiatria Danubina Volume: 22 ISSN: 0353-5053 ISO Abbreviation: Psychiatr Danub Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-21 Completed Date: 2010-08-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9424753 Medline TA: Psychiatr Danub Country: Croatia |
Other Details:
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Languages: eng Pagination: 184-9 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, University Hospital Centre Zagreb, 10000 Zagreb, Croatia. predstojnik_psi@kbc-zagreb.hr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Character Comorbidity DNA Damage / genetics, physiology Epigenesis, Genetic / genetics* Gene Expression Regulation / genetics Genetic Predisposition to Disease / genetics Homocysteine / blood Humans Mental Disorders / epidemiology*, genetics*, physiopathology Mind-Body Relations (Metaphysics) / physiology Nerve Net / physiopathology Phenotype Psychophysiologic Disorders / epidemiology*, genetics*, physiopathology Risk Factors |
| Chemical | |
Reg. No./Substance:
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454-28-4/Homocysteine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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