| Comorbidity of insomnia and depression. | |
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MedLine Citation:
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PMID: 19939713 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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During the last decade, several studies have shown that insomnia, rather than a symptom of depression, could be a medical condition on its own, showing high comorbidity with depression. Epidemiological research indicates that insomnia could lead to depression and/or that common causalities underlie the two disorders. Neurobiological and sleep EEG studies suggest that a heightened level of arousal may play a common role in both conditions and that signs of REM sleep disinhibition may appear in individuals prone to depression. The effects of antidepressant drugs on non-REM and REM sleep are discussed in relation to their use in insomnia comorbid with depression. Empirical treatment approaches are behavioral management of sleep combined with prescription of a sedative antidepressant alone, co-prescription of two antidepressants, or of an antidepressant with a hypnotic drug. |
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Authors:
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Luc Staner |
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Publication Detail:
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Type: Journal Article; Review Date: 2009-11-25 |
Journal Detail:
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Title: Sleep medicine reviews Volume: 14 ISSN: 1532-2955 ISO Abbreviation: Sleep Med Rev Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2010-04-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9804678 Medline TA: Sleep Med Rev Country: England |
Other Details:
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Languages: eng Pagination: 35-46 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier Ltd. All rights reserved. |
Affiliation:
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Sleep Laboratory, Forenap, Centre Hospitalier de Rouffach, 27 rue du 4?me R.S.M. F-68250 Rouffach, France. luc.staner@forenap.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Behavior Therapy Combined Modality Therapy Comorbidity Depressive Disorder / epidemiology* Electroencephalography Humans Hypnotics and Sedatives / therapeutic use Sleep Initiation and Maintenance Disorders / drug therapy, epidemiology*, therapy* Sleep, REM / physiology |
| Chemical | |
Reg. No./Substance:
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0/Hypnotics and Sedatives |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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