Document Detail


Community pathology of atherosclerosis and coronary heart disease: post mortem serum cholesterol and extent of coronary atherosclerosis.
MedLine Citation:
PMID:  7211824     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Little is known about the direct relationship between serum cholesterol and the extent of coronary atherosclerosis in human populations even though the association of serum cholesterol levels with risk of developing coronary heart disease (CHD) is well documented. The results of this study of men 25-44 years of age, residents of Orleans Parish, Louisiana, show a significant relationship between post mortem serum cholesterol levels and extent of more advanced lesions (raised lesions) in the coronary arteries in 110 autopsied white men, but not in the cases of 221 autopsied black men. When disease categories comprising CHD cases and non-CHD cases (basal group) were evaluated, the racial difference in the cholesterol-lesion associations persisted. The reason for the racial difference in the observed cholesterol-lesion association is not clear. Additional research, where younger age groups are included, and considering earlier lesions and other risk factors in different environments may help in clearing this question.
Authors:
M C Oalmann; G T Malcom; V T Toca; M A Guzmán; J P Strong
Related Documents :
18663154 - Oxidized low-density lipoprotein cholesterol is associated with decreases in cardiac fu...
10359814 - Myocardial infarction mediated by endothelin receptor signaling in hypercholesterolemic...
21860554 - Preoperative aspirin resistance does not increase myocardial injury during off-pump cor...
15147434 - Fluvastatin prevents cardiac death and myocardial infarction in renal transplant recipi...
19556144 - Revised cardiac risk index (lee) and perioperative cardiac events as predictors of long...
12928024 - Prognostic value of pharmacological stress echocardiography in diabetic patients.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of epidemiology     Volume:  113     ISSN:  0002-9262     ISO Abbreviation:  Am. J. Epidemiol.     Publication Date:  1981 Apr 
Date Detail:
Created Date:  1981-05-26     Completed Date:  1981-05-26     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7910653     Medline TA:  Am J Epidemiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  396-403     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Arteriosclerosis / blood,  pathology*
Autopsy
Cholesterol / blood*
Continental Population Groups
Coronary Disease / blood,  mortality,  pathology*
Humans
Louisiana
Male
Grant Support
ID/Acronym/Agency:
HL08974/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  High blood pressure and 17-year cancer mortality in the Western Electric Health Study.
Next Document:  Age-specific trends in mortality from ischemic heart disease and cerebrovascular disease in Australi...