Document Detail


Community-acquired CTX-M-15-type ESBL-producing Escherichia coli meningitis: a case report and literature review.
MedLine Citation:
PMID:  23669434     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In this report, a case of community-acquired acute bacterial meningitis (CA-ABM) caused by CTX-M-15-producing Escherichia coli in an elderly male patient was presented in the light of literature. Cultures of cerebrospinal fluid, blood, ear discharge, and stool samples yielded CTX-M-15-producing E. coli in-vitro, which was resistant to the extended-spectrum cephalosporins and ciprofloxacin and susceptible to imipenem, meropenem and amikacin. Meningitis was treated with parenteral meropenem plus parenteral and intraventricular amikacin administration. Since bacterial meningitis is a life-threatening infection, empiric antibiotic therapy with carbapenem can be started before the culture results are obtained, mainly in areas where the ESBL epidemiology is well known.
Authors:
Nazif Elaldi; Mustafa Gokhan Gozel; Fetiye Kolayli; Aynur Engin; Cem Celik; Mustafa Zahir Bakici; Haluk Vahaboglu
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Publication Detail:
Type:  Journal Article     Date:  2013-05-13
Journal Detail:
Title:  Journal of infection in developing countries     Volume:  7     ISSN:  1972-2680     ISO Abbreviation:  J Infect Dev Ctries     Publication Date:  2013  
Date Detail:
Created Date:  2013-05-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101305410     Medline TA:  J Infect Dev Ctries     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  424-31     Citation Subset:  IM    
Affiliation:
Cumhuriyet University, Sivas, Turkey. nelaldi61@yahoo.com.
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