Document Detail


Communic acids: occurrence, properties and use as chirons for the synthesis of bioactive compounds.
MedLine Citation:
PMID:  22310167     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Communic acids are diterpenes with labdane skeletons found in many plant species, mainly conifers, predominating in the genus Juniperus (fam. Cupresaceae). In this review we briefly describe their distribution and different biological activities (anti- bacterial, antitumoral, hypolipidemic, relaxing smooth muscle, etc.). This paper also includes a detailed explanation of their use as chiral building blocks for the synthesis of bioactive natural products. Among other uses, communic acids have proven useful as chirons for the synthesis of quassinoids (formal), abietane antioxidants, ambrox and other perfume fixatives, podolactone herbicides, etc., featuring shorter and more efficient processes.
Authors:
Alejandro F Barrero; M Mar Herrador; Pilar Arteaga; Jesús F Arteaga; Alejandro F Arteaga
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Publication Detail:
Type:  Journal Article     Date:  2012-02-06
Journal Detail:
Title:  Molecules (Basel, Switzerland)     Volume:  17     ISSN:  1420-3049     ISO Abbreviation:  Molecules     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100964009     Medline TA:  Molecules     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  1448-67     Citation Subset:  IM    
Affiliation:
Departamento de Química Orgánica, Facultad de Ciencias, Instituto de Biotecnología, Universidad de Granada, Campus de Fuente Nueva, s/n. 18071 Granada, Spain. afbarre@ugr.es.
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