Document Detail


Common risk factors for both arterial and venous thrombosis.
MedLine Citation:
PMID:  18275426     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Arterial and venous thromboses have traditionally been viewed as distinct conditions, with differences in risk factors, pathology and treatment. However, recent epidemiological studies have suggested associations between venous thromboembolism, arterial thromboembolism (myocardial infarction and stroke) and atherosclerosis. While several biological mechanisms might contribute to these associations, common risk factors for both arterial and venous thrombosis probably play the major role. This article summarizes the evidence for shared risk factors (clinical, biochemical and haematological) that supports this conclusion. At a practical level, it is suggested that following routine treatment of venous thromboembolism with a course of anticoagulant drugs, patients should be routinely assessed not only for risk of recurrent venous thromboembolism but also for risk of arterial thromboembolism. Appropriate lifestyle advice and medication (including aspirin) should then be considered.
Authors:
Gordon D O Lowe
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  British journal of haematology     Volume:  140     ISSN:  1365-2141     ISO Abbreviation:  Br. J. Haematol.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-15     Completed Date:  2008-05-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372544     Medline TA:  Br J Haematol     Country:  England    
Other Details:
Languages:  eng     Pagination:  488-95     Citation Subset:  IM    
Affiliation:
Division of Cardiovascular and Medical Sciences, University of Glasgow, and Haemophilia and Thrombosis Centre, Royal Infirmary, Glasgow, UK. g.d.lowe@clinmed.gla.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Estrogen Replacement Therapy / adverse effects
Female
Humans
Hypertension / complications
Metabolic Syndrome X / complications
Neoplasms / complications
Risk Factors
Smoking / adverse effects
Thrombosis / etiology*
Venous Thrombosis / etiology

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