Document Detail

Common arterial trunk: review of surgical strategies and future research.
MedLine Citation:
PMID:  22103872     Owner:  NLM     Status:  In-Data-Review    
Common arterial trunk is a congenital malformation that is relatively uncommon, representing 0.21-0.34% of congenital heart disease. Natural history, if not treated, leads to early death. Cardiac surgery has been modifying its natural course during the last 30 years by prolonging the lifespan of patients affected. Despite surgical mortality improvements over the last 10 years, morbidity still remains high, mainly due to the age of the patient, associated heart lesions, the evolution of truncal valve function and the type of conduit used for pulmonary artery reconstruction. Common arterial trunk disease still represents a significant challenge for cardiac surgeons and cardiologists regarding attempts to improve long-term outcomes and quality of life. Promising results may be achieved in the next 5 years by the tissue valve-engineering technology applied to search for the ideal conduit on the right ventricular outflow tract. This research has already started in many centers in order to reduce several unavoidable reinterventions nowadays. In this review, we will comment on the situation, focusing on the latest surgical innovations of the last 5 years.
Paolo de Siena; Mohamed Ghorbel; Qiang Chen; Deana Yim; Massimo Caputo
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Expert review of cardiovascular therapy     Volume:  9     ISSN:  1744-8344     ISO Abbreviation:  Expert Rev Cardiovasc Ther     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101182328     Medline TA:  Expert Rev Cardiovasc Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  1527-38     Citation Subset:  IM    
Bristol Royal Hospital for Children, University Hospital Bristol NHS Trust, Upper Maudlin Street, Bristol, BS2 8BJ, UK.
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