Document Detail

Common antigenic sites in human, bovine and porcine fibrinogens.
MedLine Citation:
PMID:  6167008     Owner:  NLM     Status:  MEDLINE    
Specific antisera to the A alpha, B beta and gamma chains of porcine fibrinogen were used to characterize an antigenic homology of human, bovine, and porcine fibrinogens. Antigenic determinants shared by these fibrinogens were mostly formed by the A alpha chain. However, in the case of bovine and porcine fibrinogens they were also found in the B beta and gamma polypeptide chains. The results reported here show that the A alpha chain determinants exposed on the intact fibrinogen molecule are conserved to a considerably larger extent than those of the B beta and gamma chains.
C S Cierniewski
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Thrombosis and haemostasis     Volume:  45     ISSN:  0340-6245     ISO Abbreviation:  Thromb. Haemost.     Publication Date:  1981 Apr 
Date Detail:
Created Date:  1981-09-15     Completed Date:  1981-09-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7608063     Medline TA:  Thromb Haemost     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  169-72     Citation Subset:  IM    
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MeSH Terms
Binding, Competitive
Cross Reactions
Fibrinogen / immunology*
Peptides / immunology
Swine / immunology
Reg. No./Substance:
0/Epitopes; 0/Peptides; 9001-32-5/Fibrinogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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