| Comments from the Developmental Neurotoxicology Committee of the Japanese Teratology Society on the OECD Guideline for the Testing of Chemicals, Proposal for a New Guideline 426, Developmental Neurotoxicity Study, Draft Document (October 2006 version), and on the Draft Document of the Retrospective Performance Assessment of the Draft Test Guideline 426 on Developmental Neurotoxicity. | |
| | |
MedLine Citation:
|
PMID: 17504392 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In October 2006, a new revision of the draft guideline (OECD Guideline for the Testing of Chemicals, Proposal for a New Guideline 426. Developmental Neurotoxicity Study) and Draft Document of the Retrospective Performance Assessment (RPA) of the Draft Test Guideline 426 on Developmental Neurotoxicity were distributed following incorporation of the results of the Expert Consultation Meeting in Tokyo on May 24-26, 2005. The draft guideline consists of 50 paragraphs and an appendix with 102 references; and the draft RPA consists of 37 paragraphs with 109 references. National coordinators were requested to arrange for national expert reviews of these draft documents in their member countries. Members of the Developmental Neurotoxicology (DNT) Committee of the Japanese Teratology Society (JTS) reviewed, discussed, and commented on the draft Test Guideline Proposal. The DNT Committee of the JTS also commented on the draft document of the RPA. These comments were sent to the OECD Secretariat. The DNT Committee of the JTS expects the comments to be useful for the finalization of these draft documents. |
| | |
Authors:
|
Makoto Ema; Yoshihiro Fukui; Hiroaki Aoyama; Michio Fujiwara; Junichiro Fuji; Minoru Inouye; Takayuki Iwase; Takahide Kihara; Akihide Oi; Hiroki Otani; Mitsuhiro Shinomiya; Kozo Sugioka; Tsunekazu Yamano; Keisuke H Yamashita; Takashi Tanimura; |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Congenital anomalies Volume: 47 ISSN: 0914-3505 ISO Abbreviation: Congenit Anom (Kyoto) Publication Date: 2007 Jun |
Date Detail:
|
Created Date: 2007-05-16 Completed Date: 2007-07-20 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9306292 Medline TA: Congenit Anom (Kyoto) Country: Japan |
Other Details:
|
Languages: eng Pagination: 74-6 Citation Subset: IM |
Affiliation:
|
Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences, Tokyo, Japan. ema@nihs.go.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abnormalities, Drug-Induced
/
diagnosis Developmental Biology* Female Fetus / drug effects Guidelines as Topic Hazardous Substances / toxicity* Humans Japan Pregnancy Reproduction / drug effects* Research Design / standards* Teratogens / pharmacology* Teratology* Toxicity Tests / methods*, standards* |
| Chemical | |
Reg. No./Substance:
|
0/Hazardous Substances; 0/Teratogens |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Abdominal dystocia in a case of undetected intrauterine meconium peritonitis due to cystic fibrosis.
Next Document: Evidence that down regulation of hypothalamic KiSS-1 expression is involved in the negative feedback...