Document Detail


Commentary on the use of run-in periods in clinical trials.
MedLine Citation:
PMID:  10190414     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Concerns have been raised about the applicability of clinicals trials to the so-called "real world" setting of clinical practice when such trials employ run-in periods. In fact, run-in periods are an essential part of good medical practice, and the limited practical applicability of clinical trial results relates more to their rigid artificial protocol setting.
Authors:
J A Franciosa
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Publication Detail:
Type:  Editorial    
Journal Detail:
Title:  The American journal of cardiology     Volume:  83     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-04-15     Completed Date:  1999-04-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  942-4, A9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Cardiovascular Agents / administration & dosage
Humans
Patient Selection
Randomized Controlled Trials as Topic / methods*
Research Design
Chemical
Reg. No./Substance:
0/Cardiovascular Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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