Document Detail

Commentary on the use of run-in periods in clinical trials.
MedLine Citation:
PMID:  10190414     Owner:  NLM     Status:  MEDLINE    
Concerns have been raised about the applicability of clinicals trials to the so-called "real world" setting of clinical practice when such trials employ run-in periods. In fact, run-in periods are an essential part of good medical practice, and the limited practical applicability of clinical trial results relates more to their rigid artificial protocol setting.
J A Franciosa
Related Documents :
21720894 - The impact of pharmacist interventions on osteoporosis management: a systematic review.
19828364 - The state of the art in clinical knowledge management: an inventory of tools and techni...
21673084 - Pain management and osteopathic manipulative medicine in the army: new opportunities fo...
18440434 - Protocol-driven ventilator weaning: reviewing the evidence.
22893864 - Recognition and management of abdominal injuries at athletic events.
15481344 - Treatment of hepatitis b with interferon and combination therapy.
Publication Detail:
Type:  Editorial    
Journal Detail:
Title:  The American journal of cardiology     Volume:  83     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-04-15     Completed Date:  1999-04-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  942-4, A9     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cardiovascular Agents / administration & dosage
Patient Selection
Randomized Controlled Trials as Topic / methods*
Research Design
Reg. No./Substance:
0/Cardiovascular Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Different remodeling of descending thoracic aorta after acute event in aortic intramural hemorrhage ...
Next Document:  Comparison of the prognostic value of qualitative versus quantitative stress tomographic perfusion i...