Document Detail


Commentary: the year in nuclear receptor control of metabolism.
MedLine Citation:
PMID:  20880985     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This commentary highlights some of the most important discoveries in the field of nuclear receptor control of metabolism that occurred over the past year (2009 to 2010). As might be expected in a field that encompasses several hundred active laboratories, the task of providing a balanced look at these discoveries was daunting. Thus, to help make the selection of these discoveries, a small panel of colleagues was recruited to help. After selecting the top candidate discoveries from a Google search and a PubMed search, the panel was asked to rank them. These final selections were presented at "The Year In Basic Science Session" of the Annual Meeting of the Endocrine Society, ENDO 2010, the highlights of which are reproduced in this article.
Authors:
David J Mangelsdorf
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-09-29
Journal Detail:
Title:  Molecular endocrinology (Baltimore, Md.)     Volume:  24     ISSN:  1944-9917     ISO Abbreviation:  Mol. Endocrinol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-28     Completed Date:  2011-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8801431     Medline TA:  Mol Endocrinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2075-80     Citation Subset:  IM    
Affiliation:
University of Texas Southwestern Medical Center, Howard Hughes Medical Institute, Department of Pharmacology, 6001 Forest Park Road, Room ND9.124A, Dallas, TX 75390-9050, USA. davo.mango@utsouthwestern.edu
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MeSH Terms
Descriptor/Qualifier:
Acute-Phase Reaction / immunology
Animals
Bone Resorption / metabolism
Caenorhabditis elegans / metabolism
Cholesterol / metabolism
Drosophila / metabolism
Fibroblast Growth Factors / metabolism
Heme / biosynthesis
Humans
Ketosis / metabolism
Ligands
Nuclear Reprogramming
Orphan Nuclear Receptors / metabolism
Osteogenesis
PPAR alpha / metabolism
PPAR gamma / metabolism
Pluripotent Stem Cells / metabolism
Receptors, Cytoplasmic and Nuclear / metabolism*
Reproduction
Starvation
Sumoylation
Transcription Factors / metabolism
Chemical
Reg. No./Substance:
0/Ligands; 0/Orphan Nuclear Receptors; 0/PPAR alpha; 0/PPAR gamma; 0/Receptors, Cytoplasmic and Nuclear; 0/Transcription Factors; 0/fibroblast growth factor 21; 0/liver X receptor; 0/peroxisome-proliferator-activated receptor-gamma coactivator-1; 14875-96-8/Heme; 57-88-5/Cholesterol; 62031-54-3/Fibroblast Growth Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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