Document Detail


Commentary on "Penetration of benzene, toluene and xylenes contained in gasolines through human abdominal skin in vitro".
MedLine Citation:
PMID:  17561368     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this commentary we refer to the new data recently published by Adami et al. [Adami, G., Larese, F., Venier, M., Barbieri, P., Lo Coco, F., Reisenhofer, E., 2006. Penetration of benzene, toluene and xylenes contained in gasolines through human abdominal skin in vitro. Toxicol. In Vitro 20, 1321-1330], which we acknowledge as a reliable basis for the retrospective assessment of percutaneous benzene absorption at the workplace. The data from Adami et al. (2006) are supported by the literature and by a German approach for calculating the contribution of the dermal uptake of benzene to the total body burden. This knowledge is important for the judgment of leukaemia suspected to be an occupational disease.
Authors:
Eberhard Nies; Gintautas Korinth
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Publication Detail:
Type:  Comment; Journal Article     Date:  2007-05-05
Journal Detail:
Title:  Toxicology in vitro : an international journal published in association with BIBRA     Volume:  22     ISSN:  0887-2333     ISO Abbreviation:  Toxicol In Vitro     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2007-12-24     Completed Date:  2008-03-20     Revised Date:  2009-04-10    
Medline Journal Info:
Nlm Unique ID:  8712158     Medline TA:  Toxicol In Vitro     Country:  England    
Other Details:
Languages:  eng     Pagination:  275-7     Citation Subset:  IM    
Affiliation:
BG Institute for Occupational Safety and Health (BGIA), Sub-division Toxicology of Industrial Chemicals, Alte Heerstrasse 111, 53757 Sankt Augustin, Germany.
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MeSH Terms
Descriptor/Qualifier:
Benzene / pharmacokinetics*,  toxicity
Carcinogens / pharmacokinetics*,  toxicity
Humans
Leukemia / chemically induced
Occupational Exposure / adverse effects
Permeability
Risk Assessment / methods
Skin Absorption
Chemical
Reg. No./Substance:
0/Carcinogens; 71-43-2/Benzene
Comments/Corrections
Comment On:
Toxicol In Vitro. 2006 Dec;20(8):1321-30   [PMID:  16829017 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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