Document Detail


Genetic modification through oligonucleotide-mediated mutagenesis. A GMO regulatory challenge?
MedLine Citation:
PMID:  19833073     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the European Union, the definition of a GMO is technology-based. This means that a novel organism will be regulated under the GMO regulatory framework only if it has been developed with the use of defined techniques. This approach is now challenged with the emergence of new techniques. In this paper, we describe regulatory and safety issues associated with the use of oligonucleotide-mediated mutagenesis to develop novel organisms. We present scientific arguments for not having organisms developed through this technique fall within the scope of the EU regulation on GMOs. We conclude that any political decision on this issue should be taken on the basis of a broad reflection at EU level, while avoiding discrepancies at international level.
Authors:
Didier Breyer; Philippe Herman; Annick Brandenburger; Godelieve Gheysen; Erik Remaut; Patrice Soumillion; Jan Van Doorsselaere; Ren?? Custers; Katia Pauwels; Myriam Sneyers; Dirk Reheul
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Publication Detail:
Type:  Journal Article     Date:  2009-10-16
Journal Detail:
Title:  Environmental biosafety research     Volume:  8     ISSN:  1635-7922     ISO Abbreviation:  Environ Biosafety Res     Publication Date:    2009 Apr-Jun
Date Detail:
Created Date:  2009-10-16     Completed Date:  2010-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101172622     Medline TA:  Environ Biosafety Res     Country:  France    
Other Details:
Languages:  eng     Pagination:  57-64     Citation Subset:  IM    
Affiliation:
Scientific Institute of Public Health, Division of Biosafety and Biotechnology, Brussels, Belgium. didier.breyer@iph.fgov.be
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MeSH Terms
Descriptor/Qualifier:
Animals
Animals, Genetically Modified*
European Union
Genetic Engineering / legislation & jurisprudence*,  methods*
Government Regulation*
International Cooperation
Mutagenesis*
Plants, Genetically Modified*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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