| Comment on "Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome". | |
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MedLine Citation:
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PMID: 20466906 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Lombardi et al. (Reports, 23 October 2009, p. 585) reported an association between the human gammaretrovirus XMRV and chronic fatigue syndrome. However, their results may be misleading because of various potential sources of bias and confounding. If real, the association may lack generalizability because of the specific characteristics of the cases studied and could be due to reverse causality. |
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Authors:
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Cathie Sudlow; Malcolm Macleod; Rustam Al-Shahi Salman; Jon Stone |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Science (New York, N.Y.) Volume: 328 ISSN: 1095-9203 ISO Abbreviation: Science Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-14 Completed Date: 2010-05-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0404511 Medline TA: Science Country: United States |
Other Details:
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Languages: eng Pagination: 825; author reply 825 Citation Subset: IM |
Affiliation:
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Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK. cathie.sudlow@ed.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bias (Epidemiology) Blood Cells / virology* Case-Control Studies Confounding Factors (Epidemiology) Epidemiologic Research Design Fatigue Syndrome, Chronic / epidemiology, immunology, virology* Gammaretrovirus / isolation & purification* Humans Retroviridae Infections / virology* Specimen Handling Tumor Virus Infections / virology* |
| Comments/Corrections | |
Comment On:
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Science. 2009 Oct 23;326(5952):585-9
[PMID:
19815723
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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