| Combining nefazodone and midazolam during ECT. | |
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MedLine Citation:
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PMID: 10572373 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report the case of a patient suffering from dysthymia. He underwent successful ECT treatment and was medicated with nefazodone and midazolam. Comparing the EEG and motor seizure duration in the periods with and without midazolam, no significant differences were recorded, but the dosage of thiopental and of succinylcholine had to be increased markedly after midazolam was discontinued (P < 0.05; ANOVA). This case indicates a substantial pharmacodynamic interaction between nefazodone, midazolam, thiopental, and succinylcholine. |
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Authors:
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A Conca; Z al-Dubai; P König; W Beraus |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: European psychiatry : the journal of the Association of European Psychiatrists Volume: 14 ISSN: 0924-9338 ISO Abbreviation: Eur. Psychiatry Publication Date: 1999 Oct |
Date Detail:
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Created Date: 1999-12-21 Completed Date: 1999-12-21 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9111820 Medline TA: Eur Psychiatry Country: FRANCE |
Other Details:
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Languages: eng Pagination: 360-2 Citation Subset: IM |
Affiliation:
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Department of Psychiatry I, Regional Hospital Rankweil, Austria. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antidepressive Agents, Second-Generation
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therapeutic use* Combined Modality Therapy Drug Interactions Dysthymic Disorder / therapy* Electroconvulsive Therapy / methods* Humans Hypnotics and Sedatives / therapeutic use* Male Midazolam / therapeutic use* Middle Aged Neuromuscular Depolarizing Agents / therapeutic use Succinylcholine / therapeutic use Thiopental / therapeutic use Treatment Outcome Triazoles / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Antidepressive Agents, Second-Generation; 0/Hypnotics and Sedatives; 0/Neuromuscular Depolarizing Agents; 0/Triazoles; 306-40-1/Succinylcholine; 59467-70-8/Midazolam; 76-75-5/Thiopental; 83366-66-9/nefazodone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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