Document Detail


Combining ictal surface-electroencephalography and seizure semiology improves patient lateralization in temporal lobe epilepsy.
MedLine Citation:
PMID:  11114215     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The study goal was to assess the concordance of ictal surface-EEG and seizure semiology data in lateralizing intractable temporal lobe epilepsy (TLE) and to examine the benefits of the combined use of these two methods. METHODS: We independently analyzed the ictal recordings and clinical symptoms associated with 262 seizures recorded in 59 TLE patients. Each seizure was lateralized on the basis of (i) its associated ictal surface-EEG pattern according to a predefined lateralization protocol and (ii) its associated ictal and postictal seizure semiology according to strictly defined clinical criteria. Individual patients were also lateralized based on these data. RESULTS: Ictal surface-EEG findings lateralized 62.6% of seizures and 64.4% of patients. Seizure semiology findings lateralized 46.2% of seizures and 78.0% of patients. There was a high degree of concordance between lateralizations based on these two methods, for both individual seizures and individual patients. Combination of the information from the two methods allowed for lateralization in a greater proportion of both seizures (79.8%) and patients (94.9%). Combined EEG-seizure lateralization was concordant with the side of operation in 33 of 34 patients who underwent successful surgery (Engel's surgical outcome class I/II). CONCLUSIONS: In TLE, there is a high agreement between the lateralization of individual seizures and patients, which is based on ictal surface-EEG findings and seizure semiology. Furthermore, combination of these two methods improves the lateralization of individual seizures and patients. Thus, standardized combined EEG-seizure analysis is a valuable noninvasive tool in the presurgical evaluation of TLE.
Authors:
W Serles; Z Caramanos; G Lindinger; E Pataraia; C Baumgartner
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Epilepsia     Volume:  41     ISSN:  0013-9580     ISO Abbreviation:  Epilepsia     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2000-12-29     Completed Date:  2001-02-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2983306R     Medline TA:  Epilepsia     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1567-73     Citation Subset:  IM    
Affiliation:
Universitätsklinik für Neurologie, Vienna, Austria. wolfgang.serles@akh-wien.ac.at
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MeSH Terms
Descriptor/Qualifier:
Adult
Automatism / diagnosis,  physiopathology
Electroencephalography / statistics & numerical data*
Epilepsy, Temporal Lobe / diagnosis*,  physiopathology,  surgery
Female
Functional Laterality / physiology*
Humans
Magnetic Resonance Imaging / statistics & numerical data
Male
Middle Aged
Retrospective Studies
Temporal Lobe / physiopathology*,  surgery
Treatment Outcome
Videotape Recording

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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