| Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors. | |
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MedLine Citation:
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PMID: 17490962 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Regular exercise and consuming long-chain n-3 fatty acids (FAs) from fish or fish oil can independently improve cardiovascular and metabolic health, but combining these lifestyle modifications may be more effective than either treatment alone. OBJECTIVE: We examined the individual and combined effects of n-3 FA supplements and regular exercise on body composition and cardiovascular health. DESIGN: Overweight volunteers [body mass index (BMI; in kg/m(2)): >25] with high blood pressure, cholesterol, or triacylglycerols were randomly assigned to one of the following interventions: fish oil (FO), FO and exercise (FOX), sunflower oil (SO; control), or SO and exercise (SOX). Subjects consumed 6 g tuna FO/d ( approximately 1.9 g n-3 FA) or 6 g SO/d. The exercise groups walked 3 d/wk for 45 min at 75% age-predicted maximal heart rate. Plasma lipids, blood pressure, and arterial function were assessed at 0, 6, and 12 wk. Body composition was assessed by dual-energy X-ray absorptiometry at 0 and 12 wk only. RESULTS: FO supplementation lowered triacylglycerols, increased HDL cholesterol, and improved endothelium-dependent arterial vasodilation (P<0.05). Exercise improved arterial compliance (P<0.05). Both fish oil and exercise independently reduced body fat (P<0.05). CONCLUSIONS: FO supplements and regular exercise both reduce body fat and improve cardiovascular and metabolic health. Increasing intake of n-3 FAs could be a useful adjunct to exercise programs aimed at improving body composition and decreasing cardiovascular disease risk. |
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Authors:
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Alison M Hill; Jonathan D Buckley; Karen J Murphy; Peter R C Howe |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of clinical nutrition Volume: 85 ISSN: 0002-9165 ISO Abbreviation: Am. J. Clin. Nutr. Publication Date: 2007 May |
Date Detail:
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Created Date: 2007-05-10 Completed Date: 2007-06-14 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376027 Medline TA: Am J Clin Nutr Country: United States |
Other Details:
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Languages: eng Pagination: 1267-74 Citation Subset: AIM; IM |
Affiliation:
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Nutritional Physiology Research Centre and the Australian Technology Network Centre for Metabolic Fitness, University of South Australia, Adelaide, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Absorptiometry, Photon Adipose Tissue / drug effects, metabolism Adult Aged Blood Pressure / drug effects, physiology Body Composition / drug effects*, physiology Cardiovascular Diseases / blood, epidemiology*, prevention & control Combined Modality Therapy Dietary Supplements Endothelium, Vascular / drug effects Exercise / physiology* Female Fish Oils / administration & dosage* Humans Lipid Metabolism / drug effects*, physiology Male Middle Aged Plant Oils / administration & dosage Risk Factors Triglycerides / blood Vasodilation / drug effects, physiology Weight Loss / drug effects, physiology |
| Chemical | |
Reg. No./Substance:
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0/Fish Oils; 0/Plant Oils; 0/Triglycerides; 8001-21-6/sunflower seed oil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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