Document Detail

Combined use of color duplex ultrasonography and B-flow imaging for evaluation of patients with carotid artery stenosis.
MedLine Citation:
PMID:  15569764     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: Color duplex ultrasonography (CDU) is a standard method of noninvasive evaluation of internal carotid artery stenosis (ICAS). B-flow imaging (BFI), on the other hand, is a newer method. We investigated the accuracy of the two noninvasive tests--CDU and BFI--each separately and as a combination of the two tests by comparing with digital subtraction angiography as a reference standard. METHODS: We performed CDU, BFI, and digital subtraction angiography on 95 consecutive patients with ICAS. Separate and combined test results of CDU and BFI were compared with digital subtraction angiography results. RESULTS: For identifying 70% to 99% ICAS, as CDU criterion, the ratio of internal carotid artery to common carotid artery peak systolic velocity had the highest diagnostic accuracy (sensitivity, 94%; specificity, 96%). The sensitivity and specificity of BFI were 65% and 98%, respectively. With CDU and BFI, results were concordant in 144 (89%) cases for 70% to 99% ICAS. Sensitivity and specificity of combined CDU and BFI results for identification of ICAS were 95% and 99%, respectively. The misclassification rates of CDU and BFI were 4.7% and 8.1%, respectively. When combined test results were concordant, the misclassification rate decreased to 1.4%. CONCLUSION: CDU showed a slightly better accuracy than did BFI in the diagnosis of carotid artery stenosis. Combined use of CDU and BFI is more accurate than use of either test alone.
Muharrem Tola; Mehmet Yurdakul; Turhan Cumhur
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article    
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  25     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:    2004 Nov-Dec
Date Detail:
Created Date:  2004-11-30     Completed Date:  2005-02-08     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1856-60     Citation Subset:  IM    
Department of Radiology, Türkiye Yüksek Ihtisas Hospital, Kizilay Sokak No: 4, 06100 Sihhiye, Ankara, Turkey.
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MeSH Terms
Aged, 80 and over
Angiography, Digital Subtraction
Blood Flow Velocity
Carotid Arteries / physiopathology
Carotid Artery, Internal / radiography,  ultrasonography*
Carotid Stenosis / radiography,  ultrasonography*
Cerebral Angiography
Middle Aged
Rheology / methods*
Sensitivity and Specificity
Ultrasonography / methods*,  standards
Ultrasonography, Doppler, Color* / standards

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