| Combined use of beta-sympathomimetic drugs and beta-blockers during labour. | |
| | |
MedLine Citation:
|
PMID: 7247466 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
None of the betamimetics have a exclusively tocolytic effect. By stimulating the cardiovascular beta-receptor, they also cause a substantial increase in the heart rate and a decrease in blood pressure. We administered 4--5 micrograms/min of Fenoterol to 13 patients during the first stage of labour. This led to complete inhibition of labour. To reduce cardiac side effects, a primarily cardiac beta-blocker (5 mg Atenolol or 20 mg Metoprolol) was also given. The maternal and fetal heart rates were measured by ECG and by fetal scalp-electrode, respectively. The fetal heart rate remained largely unchanged, both during the Fenoterol infusion as well as during the additional administration of the beta-blocker. The maternal heart rate, which increased under the influence of the Fenoterol, fell (p less than or equal to 0.01) but did not return to normal. In all cases the beta-blockade led to a brief increase in uterine activity. |
| | |
Authors:
|
M Steyer; W Poleska; H P Diemer; H Schmidt; J Heidenreich |
Related Documents
:
|
23457266 - A study examining rates of medical staff recognition of pressure ulceration in hospital... 21221256 - Hypertension case-finding in a rural family practice clinic: a look at the effectivenes... 2572366 - Acute changes in the properties of baroreflexes in man after beta-blockade. 7870896 - Beta-receptor responsiveness after desipramine treatment. 8475736 - The relationship between nasal airway resistance and middle ear pressure in subjects wi... 23108786 - Evaluation of n95 respirator use with a surgical mask cover: effects on breathing resis... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Archives of gynecology Volume: 230 ISSN: 0170-9925 ISO Abbreviation: Arch. Gynecol. Publication Date: 1981 |
Date Detail:
|
Created Date: 1981-08-20 Completed Date: 1981-08-20 Revised Date: 2005-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7901051 Medline TA: Arch Gynecol Country: GERMANY, WEST |
Other Details:
|
Languages: eng Pagination: 231-7 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Atenolol
/
therapeutic use* Blood Pressure / drug effects Ethanolamines / therapeutic use* Female Fenoterol / adverse effects, therapeutic use* Heart Rate / drug effects Humans Metoprolol / therapeutic use* Obstetric Labor Complications / drug therapy* Pregnancy Propanolamines / therapeutic use* Tachycardia / chemically induced, drug therapy |
| Chemical | |
Reg. No./Substance:
|
0/Ethanolamines; 0/Propanolamines; 13392-18-2/Fenoterol; 29122-68-7/Atenolol; 37350-58-6/Metoprolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Comparison of breast tumours evaluated by ultrasound, mammography, and clinical investigation.
Next Document: Morphology of rabbit oviduct after microsurgical techniques for reanastomosis of the isthmus or ampu...