Document Detail

Combined use of alpha-fetoprotein and ultrasound in the prenatal diagnosis of arteriovenous fistula in the brain.
MedLine Citation:
PMID:  2442685     Owner:  NLM     Status:  MEDLINE    
A case of arteriovenous fistula in the brain detected by the combined use of maternal serum alpha-fetoprotein (AFP) and ultrasound in the third trimester of pregnancy is described. The maternal serum AFP concentration at 34 weeks of gestation was 300 ng/mL (2.3 times the median). Stage II diagnostic ultrasonography at 37 weeks revealed a large midline cystic mass, contiguous to a normal-appearing lateral ventricle and surrounded by an abnormal heterogeneous zone of increased echogenicity. At birth, the cord blood AFP concentration was 2 SD above the mean. Subsequent histopathologic examination revealed a vein of Galen aneurysm and fistula in the brain.
G J Mizejewski; S Polansky; F A Mondragon-Tiu; A M Ellman
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  70     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1987 Sep 
Date Detail:
Created Date:  1987-09-25     Completed Date:  1987-09-25     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  452-3     Citation Subset:  AIM; IM    
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MeSH Terms
Fetal Diseases / diagnosis*
Intracranial Arteriovenous Malformations / diagnosis*
Prenatal Diagnosis*
alpha-Fetoproteins / analysis*
Reg. No./Substance:

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