Document Detail

Combined tinidazole and doxycycline prophylaxis in colorectal surgery. An interhospital trial.
MedLine Citation:
PMID:  6988948     Owner:  NLM     Status:  MEDLINE    
There were no significant differences between randomized groups on either preoperative tinidazole or placebo added to pre-, per, and postoperative doxycycline. Cases of anaerobic infection among the placebos patients as well as a general trend of the parameters studied suggest that tinidazole gives added protection, i.e. that antibiotic prophylaxis should also comprise anaerobic microbes.
O P Grüner; O Holter; A Baardsen
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Scandinavian journal of gastroenterology. Supplement     Volume:  59     ISSN:  0085-5928     ISO Abbreviation:  Scand. J. Gastroenterol. Suppl.     Publication Date:  1980  
Date Detail:
Created Date:  1980-06-25     Completed Date:  1980-06-25     Revised Date:  2008-02-13    
Medline Journal Info:
Nlm Unique ID:  0437034     Medline TA:  Scand J Gastroenterol Suppl     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  25-8     Citation Subset:  IM    
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MeSH Terms
Clinical Trials as Topic
Colon / surgery*
Doxycycline / therapeutic use*
Middle Aged
Nitroimidazoles / therapeutic use*
Postoperative Care
Random Allocation
Rectum / surgery*
Surgical Wound Infection / prevention & control*
Tinidazole / therapeutic use*
Reg. No./Substance:
0/Nitroimidazoles; 0/Placebos; 19387-91-8/Tinidazole; 564-25-0/Doxycycline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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